Table 2.

Biodistribution data of [⁶⁸Ga]Ga-DATA^5m.SA.FAPi in U87MG and PC3 xenografts, 1 h, 2 h, and 3 h along with blocking experiments 2 h after injection

	U87MG				PC3
Organ	1 h	2 h	3 h	2-h blocking	1 h	2 h	3 h	2-h blocking
Blood	11.3 ± 0.9	6.6 ± 0.5	5.0 ± 0.7	0.4 ± 0.1	8.2 ± 0.8	6.2 ± 0.9	3.9 ± 0.6	0.8 ± 0.0
Heart	5.6 ± 0.8	3.7 ± 0.6	3.5 ± 1.4	0.4 ± 0.0	3.1 ± 0.4	2.6 ± 0.1	2.2 ± 0.3	0.5 ± 0.1
Liver	3.6 ± 0.4	3.5 ± 0.2	3.1 ± 1.0	0.3 ± 0.0	2.7 ± 0.4	2.5 ± 0.3	2.4 ± 0.1	0.4 ± 0.0
Spleen	2.8 ± 0.7	1.9 ± 0.3	1.8 ± 0.2	0.3 ± 0.1	2.1 ± 0.3	1.6 ± 0.1	2.1 ± 0.7	0.6 ± 0.1
Lung	4.6 ± 0.9	3.3 ± 0.3	2.5 ± 0.2	0.9 ± 0.2	3.6 ± 0.7	2.7 ± 0.5	2.5 ± 0.5	0.6 ± 0.1
Kidney	4.6 ± 0.4	3.6 ± 0.7	3.7 ± 1.1	1.3 ± 0.2	3.2 ± 0.4	2.5 ± 0.4	2.5 ± 0.4	0.9 ± 0.1
Stomach	2.2 ± 0.8	1.8 ± 0.4	1.8 ± 0.5	0.4 ± 0.1	2.0 ± 0.4	1.6 ± 0.3	2.0 ± 0.3	0.4 ± 0.1
Intestine	5.1 ± 1.0	4.6 ± 1.8	4.9 ± 0.6	1.2 ± 0.7	4.2 ± 0.8	3.2 ± 0.8	2.8 ± 0.1	0.9 ± 0.0
Pancreas	9.9 ± 3.2	7.1 ± 1.3	6.9 ± 1.0	0.5 ± 0.1	7.4 ± 1.9	5.3 ± 0.3	3.7 ± 0.6	0.3 ± 0.1
Muscle	4.2 ± 0.9	2.8 ± 0.8	3.5 ± 0.9	1.3 ± 1.4	2.0 ± 0.3	2.0 ± 0.2	2.2 ± 0.2	0.4 ± 0.1
Bone	4.5 ± 1.4	4.7 ± 1.2	6.1 ± 1.2	2.0 ± 0.3	3.2 ± 0.9	2.5 ± 0.4	5.7 ± 0.3	1.5 ± 0.9
Tumor	6.6 ± 1.6	6.0 ± 1.0	5.4 ± 1.0	1.1 ± 0.4	5.0 ± 0.6	4.6 ± 0.8	4.7 ± 0.3	0.7 ± 0.0
Tumor/blood	0.6 ± 0.2	0.9 ± 0.2	1.1 ± 0.4		0.6 ± 0.1	0.7 ± 0.1	1.2 ± 0.2
Tumor/liver	1.8 ± 0.5	1.7 ± 0.2	1.7 ± 0.2		1.9 ± 0.4	1.8 ± 0.1	1.9 ± 0.2
Tumor/kidney	1.4 ± 0.4	1.7 ± 0.4	1.5 ± 0.3		1.6 ± 0.3	1.8 ± 0.1	1.9 ± 0.1
Tumor/muscle	1.6 ± 0.5	2.1 ± 0.7	1.5 ± 0.3		2.5 ± 0.1	2.2 ± 0.2	2.1 ± 0.1
Tumor/pancreas	0.7 ± 0.2	0.9 ± 0.3	0.8 ± 0.4		0.7 ± 0.3	0.9 ± 0.1	1.3 ± 0.3

Data are expressed in percentage of injected activity per gram of tissue (% IA/g) and are presented as the mean ± SD (n = 4)