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. 2023 Sep 15;29(10):gaad033. doi: 10.1093/molehr/gaad033

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© The Author(s) 2023. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Volcano plots comparing cumulus cell differentially expressed genes for Type 2, 3, and 4 versus 1 ovulatory-size follicles in the small ovarian reserve heifer. Volcano plots of cumulus cell transcriptome data noting locations of the 17 DEGs described in this analysis. Data are from the previously published transcriptome study (Clark et al., 2022b). The panels show data for the comparisons noted above each panel (left to right, Type 2, 3, and 4 versus Type 1). Each panel plots the Log₂(foldchange) along the x axis, and the −Log₁₀ (FDR) from the DESeq2 output from our previous study (Clark et al., 2022b). Horizontal dashed lines denote two FDR thresholds: 0.01 and 0.05. Point color key: black = non-DEG; red = upregulated DEGs; blue = downregulated DEGs. The 17 DEGs common to all follicle types are indicated by their gene symbols. DEGs, differentially expressed genes; FDR, false discovery rate.