Table 2.
Patient and tumor characteristics at the time of first RS and second RS testing in the study cohort.
| First BC n = 60 | Second BC n = 60 | p* | |
|---|---|---|---|
| Median (IQR) age at testing, years | 55.5 (44–62) | 60.5 (50–67) | <0.001 |
| Median (IQR) tumor size, cm | 1.6 (1.1–2.2) | 1.4 (1.0–1.8) | 0.54 |
| Tumor size category, n (%) | 0.096a | ||
| ≤1 cm | 15 (25.0%) | 16 (26.7%) | |
| >1-2 cm | 27 (45.0%) | 32 (53.3%) | |
| >2 cm | 18 (30.0%) | 9 (15.0%) | |
| Not available | 0 (0%) | 3 (5.0) | |
| Tumor grade category, n (%) | 0.79b | ||
| Grade 1 | 9 (15.0%) | 6 (10.0%) | |
| Grade 2 | 32 (53.3%) | 36 (60.0%) | |
| Grade 3 | 10 (16.7%) | 9 (15.0%) | |
| Not available | 9 (15.0%) | 9 (15.0%) | |
| Histology, n (%) | 0.75c | ||
| IDC | 50 (83.3%) | 48 (80.0%) | |
| ILC | 5 (8.3%) | 10 (16.7%) | |
| Mucinous/colloid/papillary | 2 (3.3%) | 1 (1.7%) | |
| Other/not available | 3 (5.0%) | 1 (1.7%) | |
| Nodal status, n (%) | 0.21d | ||
| N0 | 46 (76.7%) | 49 (81.7%) | |
| N1mi | 8 (13.3%) | 1 (1.7%) | |
| N1 | 6 (10.0%) | 7 (11.7%) | |
| Not available | 0 (0.0%) | 3 (5.0%) | |
BC breast cancer, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, IQR interquartile range.
*p value for Wilcoxon signed-rank test and the McNemar’s test for continuous and categorical variables, respectively. Bolded p values are statistically significant. McNemar’s test contingency tables are presented in Supplementary Table 1.
aFor comparing tumor size ≥2 cm to <2 cm.
bFor comparing grade 1/2 to grade 3.
cFor comparing IDC to non-IDC histologies.
dFor comparing N0 to N1/N1mi patients.