A10 ANITA1.

Methods	RCT: 1994 to 2000
Participants	463 patients Stage IB‐IIIA
Interventions	surgery vs surgery + chemotherapy 4 cycles of chemotherapy cisplatin 100 mg/m2 vinorelbine 180 mg/m2 Complete resection
Outcomes	Overall survival
Notes	840 patients randomised in trial, 436 patients relevant to this trial comparison
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Data checks on IPD provided suggest adequate sequence generation
Allocation concealment (selection bias)	Low risk	Central computer randomisation
Selective reporting (reporting bias)	Low risk	IPD supplied for outcomes
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Trial not blinded due to nature of intervention, outcome not likely to be influenced by lack of blinding
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Trial not blinded due to nature of intervention, primary outcome not likely to be influenced by lack of blinding