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[Preprint]. 2023 Nov 13:2023.09.22.559017. Originally published 2023 Sep 23. [Version 2] doi: 10.1101/2023.09.22.559017

PMC10542156.1; 2023 Sep 23
PMC10542156.2; 2023 Nov 13

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Figure 1. — The six Glucuronoxylomannan (GXM) motifs that build up fungal exo-PS and capsular-PS. GXM is composed of a combination of six repeating units (M1–6), defined by a glucuronic acid (GlcA) residue every 3rd mannose with varying xylose substitutions. These 6 motifs of GXM in various combinations correlate to different serotype activities¹⁹. C. neoformans H99 serotype A has a dominant M2 motif in exo- and capsular-PS²⁰. Polysaccharide molecules can be heteropolymers composed of more than one triad¹⁷. Image created with DrawGlycan-SNFG²¹.