Table 2.

An. gambiae s.s. survival post feeding on different IVM concentrations spiked in glucose solution mixed with blood in different proportions 1:1 (A), 1:2 (B), 1:4 (C), and 1:8 (D)

A. Ivermectin bio-efficacy in 1:1 (Blood: Glucose solution)
Treatment	N	n	HR	95% CI	p-value
IVM 85 ng/ml	3	139	12.99	8.64–19.53	< 0.001
IVM 64 ng/ml	3	149	10.49	6.99–15.75	< 0.001
IVM 43 ng/ml	3	143	7.44	4.94–11.20	< 0.001
IVM 21 ng/ml	3	143	4.79	3.16–7.26	< 0.001
No IVM—Control	3	150	1	–	–

B. Ivermectin bio-efficacy in 1: 2 (Blood: Glucose solution)
Treatment	N	n	HR	95% CI	p-value
IVM 85 ng/ml	3	133	9.37	6.43–13.65	< 0.001
IVM 64 ng/ml	3	145	5.35	3.67–7.79	< 0.001
IVM 43 ng/ml	3	137	5.16	3.53–7.53	< 0.001
IVM 21 ng/ml	3	145	3.76	2.57–5.51	< 0.001
No IVM—Control	3	127	1	–	–

C. Ivermectin bio-efficacy in 1: 4 (Blood: Glucose solution)
Treatment	N	n	HR	95% CI	p-value
IVM 85 ng/ml	3	150	6.42	4.57–9.01	< 0.001
IVM 64 ng/ml	3	157	6.83	4.88–9.55	< 0.001
IVM 43 ng/ml	3	156	6.41	4.58–8.98	< 0.001
IVM 21 ng/ml	3	150	4.32	3.07–6.08	< 0.001
No IVM—Control	3	150	1	–	–

D. Ivermectin bio-efficacy in 1: 8 (Blood: Glucose solution)
Treatment	N	n	HR	95% CI	p-value
IVM 85 ng/ml	3	147	6.48	3.93–10.70	< 0.001
IVM 64 ng/ml	3	148	6.06	3.67–10.02	< 0.001
IVM 43 ng/ml	3	148	3.60	2.14–6.06	< 0.001
IVM 21 ng/ml	3	150	3.04	1.80–5.14	< 0.001
No IVM—Control	3	149	1	–	–

N number of replicates, n total number of mosquitoes, HR hazard ratios, CI confidence intervals

Log rank test comparing survival of An. gambiae s.s. mosquitoes after feeding on different IVM concentrations spiked in glucose solution mixed with blood in different proportions 1:1 (A), 1:2 (B), 1:4 (C), and 1:8 (D)