Table 3.

Serum tests and exhaled breath condensates of the exposed and control participants in the cold and warm seasons

Variable	Cold season			Warm season
	Exposed (n = 39)	Control (n = 28)	p	Exposed (n = 39)	Control (n = 28)	p
Serum test
IL-1β, pg/mL	0.6 [0.2, 2.0]	0.4 [0.0, 4.1]	0.890	7.5 [7.0, 8.2]	1.0 [0.0, 7.5]	<0.001
IL-6, pg/mL	4.8 [2.7, 9.7]	0.9 [0.1, 2.6]	<0.001	10.5 [8.0, 14.2]	8.8 [2.6, 15.5]	0.101
IL-8, pg/mL	5.3 [3.5, 10.0]	2.1 [0.0, 12.7]	0.170	20.5 [18.0, 22.5]	15.2 [10.9, 19.3]	0.009
IL17-A, pg/mL	2.9 [2.3, 3.7]	0.3 [0.0, 0.6]	<0.001	10.0 [9.0, 11.7]	2.0 [0.4, 7.5]	<0.001
TNF-α, pg/mL	2.9 [2.3, 3.7]	0.7 [0.1, 1.4]	<0.001	9.7 [8.0, 12.3]	2.5 [0.9, 10.0]	0.001
hsCRP, ng/mL	2066 [822, 4516]	1264 [184, 2238]	0.032	1187 [588, 2087]	911 [273, 2212]	0.403
PAI-1, ng/mL	10.5 [9.2, 11.3]	15.2 [8.6, 29.1]	0.078	21.2 [18.3, 22.6]	18.8 [15.5, 23.7]	0.223
8-OhdG, ng/mL	12.3 [8.9, 19.9]	14.5 [10.2, 26.3]	0.233	8.9 [7.2, 14.5]	13.1 [8.8, 24.1]	0.035
Exhaled breath condensate
IL-1β, pg/mL	1.9 [1.1, 2.4]	2.5 [0.8, 3.0]	0.469	2.3 [1.9, 3.4]	1.9 [1.1, 4.2]	0.369
IL-6, pg/mL	6.3 [5.9, 7.3]	0.0 [0.0, 0.7]	<0.001	7.6 [7.4, 9.6]	9.4 [8.6, 10.8]	0.121
IL-8, pg/mL	0.0 [0.0, 0.0]	11.9 [0.3, 23.1]	<0.001	5.3 [4.7, 7.3]	8.3 [7.3, 11.3]	0.002
IL-17A, pg/mL	0.7 [0.3, 2.4]	0.8 [0.0, 1.1]	0.110	3.0 [2.8, 3.4]	2.8 [2.5, 3.6]	0.223
MCP-1, pg/mL	3.0 [1.3, 5.2]	1.5 [0.8, 1.8]	<0.001	4.5 [4.0, 4.8]	4.5 [4.3, 5.3]	0.457

Data were presented as median (25^th and 75^th percentiles)

Abbreviations: IL, interleukin; TNF-α, tumor necrosis factor-alpha; hs-CRP, high-sensitivity C-reactive protein; PAI-1, plasminogen activator inhibitor-1; 8-OHdG, 8-hydroxy-2-deoxyguanosine; MCP-1, monocyte chemoattractant protein-1