TABLE 2.
Patient demographicsa
| Demographic characteristic | Value |
|---|---|
| Gender (no. [%] of patients) | |
| Male | 39 (89) |
| Female | 5 (11) |
| Race (no. [%] of patients) | |
| Caucasian | 32 (73) |
| African American | 4 (9) |
| Hispanic | 7 (16) |
| American Indian | 1 (2) |
| Risk factor (no. [%] of patients) | |
| Homosexual activity | 28 (64) |
| Intravenous drug use | 7 (16) |
| Other/unknown | 9 (20) |
| Clinical situation (mean ± SD [range]) | |
| Age (yr)b | 38.6 ± 7.13 (27–56) |
| Wt (kg)b | 79.1 ± 15.0 (46.5–123) |
| CLCR (ml/min)b,c | 89.1 ± 21.5 (53.6–146) |
a
A total of 44 patients were studied. Thirty-nine of the 44 patients were concomitantly receiving zidovudine. CD4 counts ranged from 6 to 540 cells/mm3 (mean, 165 cells/mm3) in a subset of these patients.
b
Value at the time that the first plasma sample was obtained.
c
CLCR, creatinine clearance. (calculated [Cockcroft-Gault]).