Table 4.
The addition of LAR improved the predictive ability of the scoring system for mortality.
| Index | AUC (95% CI) | IDI (%) (95% CI) | P-value | NRI (%) (95% CI) | P-value |
|---|---|---|---|---|---|
| Hospital mortality | |||||
| LAR | 0.63 (0.58–0.67) | – | – | – | – |
| SOFA | 0.62 (0.57–0.67) | Ref. | Ref. | Ref. | Ref. |
| SAPSⅡ | 0.68 (0.64–0.73) | Ref. | Ref. | Ref. | Ref. |
| LAR + SOFA | 0.64 (0.59–0.68) | 2.03 (0.77–3.30) | 0.002 | 31.10 (15.25–46.95) | <0.001 |
| LAR + SAPSⅡ | 0.70 (0.66–0.74) | 2.79 (1.14–4.45) | < 0.001 | 19.84 (4.69–34.99) | 0.010 |
| ICU mortality | |||||
| LAR | 0.65 (0.60–0.70) | – | – | – | – |
| SOFA | 0.66 (0.61–0.71) | Ref. | Ref. | Ref. | Ref. |
| SAPSⅡ | 0.68 (0.63–0.73) | Ref. | Ref. | Ref. | Ref. |
| LAR + SOFA | 0.67 (0.62–0.72) | 2.63 (0.96–4.29) | 0.002 | 31.61 (14.23–48.99) | <0.001 |
| LAR + SAPSⅡ | 0.71 (0.66–0.75) | 3.90 (1.85–5.95) | < 0.001 | 29.69 (12.79–46.58) | <0.001 |
AUC, area under the curve; CI, confidence interval; IDI, integrated discrimination improvement; NRI, net reclassification improvement index; LAR, lactate to albumin ratio; SOFA, Sequential Organ Failure Assessment; SAPS II, Simplifed acute physiological score II; Ref., reference.