Fig. 3.

Intravenously administered GM-CSF-IL-7-VNP20009 enriched within tumor. (A) The tissue homogenate resistant plate images showed the different enrichment of GM–CSF–IL-7-VNP20009 in major organs and tumors at different time points after administration. (B) The number of GM–CSF–IL-7-VNP20009 clones in tumors and major organs over time (n = 3). Error bar, mean ± s.d. (C) VNP20009 16s rRNA qPCR detection reflected the amount of GM–CSF–IL-7-VNP20009 in major organs and tumors at different time points after administration (n = 3). Error bar, mean ± s.d. ****P < 0.0001. The statistics were analyzed by one-way ANOVA with Tukey test.