Table 2.
Description of nodal marginal zone lymphoma cases with increased T follicular helper cells
| Case number | Age | Sex | Disease localization | Clonality | NGS | Cytogenetics/FISH |
|---|---|---|---|---|---|---|
| LYWS-1031 | 60 | M | Multiple | B+, T− | NOTCH2, CREBBP, and KLF2 mutations | MYC BA negative |
| LYWS-1037 | 53 | F | Axillary | B+, T− | Negative for TET2, RHOA, DNMT3A, and IDH2 mutations | n.a. |
| LYWS-1039 | 77 | F | Multiple | B+, T− | NOTCH2 and KLF2 mutations |
Abnormal karyotype FISH negative for IGH and TCL1A rearrangements |
| LYWS-1051 | 60 | F | Axillary, inguinal, kidney | B+, T− | CD70, IRF4, TMSB4X, and BTG2 mutations | n.a. |
| LYWS-1082 | 78 | F | Inguinal, pelvic | B+, T− | n.a. | n.a. |
| LYWS-1168 | 91 | F | Mediastinal and hilar | B+, T− | NOTCH2, CCND3, IRF8, and NOTCH1 mutations | n.a. |
| LYWS-1347 | 55 | F | Multiple | B+, T− | SPEN (2x) and TNFAIP3 mutations |
Negative for t(11;14) t(14;18) BCL6 :: MALT1 rearrangement |
| LYWS-1433 | 57 | F | Inguinal | B+, T− | Negative for mutations in MYD88 |