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. Author manuscript; available in PMC: 2023 Oct 2.
Published in final edited form as: N Engl J Med. 2022 Jul 14;387(2):148–159. doi: 10.1056/NEJMoa2119660

Figure 3. Adverse Events and Serious Adverse Events.

Figure 3.

Intracranial hemorrhage was defined as intraparenchymal or intraventricular blood seen on ultrasonography or MRI of the head. Cardiac compromise was defined as an elevated troponin level or decreased cardiac function on echocardiography. Thrombocytopenia was defined as a platelet count of less than 100,000 per cubic millimeter. Neutropenia was defined as an absolute neutrophil count of less than 1500 per cubic millimeter. Acute kidney injury was defined as a plasma creatinine level of more than 1.5 times the baseline level. Acute liver injury was defined as a serum aspartate aminotransferase level of more than 200 U per liter or a serum alanine aminotransferase level of more than 100 U per liter.