Table 2.

Multivariate Cox regression analysis of the TyG index and all-cause and CVD mortality.

	No. deaths (%)	Crude	Model 1	Model 2	Model 3
		HR (95% CI), p value	HR (95% CI), p value	HR (95% CI), p value	HR (95% CI), p value
All-cause mortality
TyG index
≤ 8.72	203 (26.92)	1 (Ref)	1 (Ref)	1 (Ref)	1 (Ref)
8.72–9.15	186 (25.14)	0.77 (0.63, 0.94), 0.011	0.76 (0.62, 0.93), 0.007	0.79 (0.65, 0.97), 0.022	0.80 (0.65, 0.98), 0.030
9.15–9.65	229 (30.25)	0.88 (0.73, 1.06), 0.175	0.88 (0.73, 1.07), 0.200	0.87 (0.72, 1.06), 0.161	0.88 (0.72, 1.08), 0.213
> 9.65	265 (35.48)	0.97 (0.80, 1.16), 0.718	1.09 (0.91, 1.32), 0.349	1.14 (0.94, 1.38), 0.172	1.14 (0.91, 1.41), 0.250
P for trend		0.776	0.108	0.07	0.174
Cardiovascular mortality
TyG index
≤ 8.72	67 (8.89)	1 (Ref)	1 (Ref)	1 (Ref)	1 (Ref)
8.72–9.15	52 (7.03)	0.65 (0.46, 0.94), 0.022	0.64 (0.44, 0.92), 0.015	0.70 (0.48, 1.01), 0.055	0.69 (0.48, 1.00), 0.052
9.15–9.65	62 (8.19)	0.72 (0.51, 1.01), 0.060	0.71 (0.50, 1.00), 0.051	0.74 (0.52, 1.05), 0.091	0.72 (0.50, 1.04), 0.081
> 9.65	84 (11.24)	0.93 (0.67, 1.28), 0.644	1.03 (0.74, 1.43), 0.851	1.12 (0.80, 1.57), 0.506	1.04 (0.70, 1.53), 0.857
P for trend		0.943	0.575	0.38	0.833

CVD, cardiovascular disease; HR, hazard ratio; CI, confidence interval; Ref, reference.

Crude: unadjusted;

Model 1: corrected for age, sex, education level, PIR and BMI;

Model 2: Model 1 + race/ethnicity, smoking status, alcohol consumption status, CHD, HF, heart attack, stroke and angina;

Model 3: Model 2 + hypertension, hyperlipidemia, glucose-lowering medication use, HbA1c, LDL-C and TC.