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. 2015 Nov 11;2015(11):CD010435. doi: 10.1002/14651858.CD010435.pub2

Comparison 1. Adjunctive steroid versus control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 All‐cause death until hospital discharge 2 132 Risk Difference (M‐H, Fixed, 95% CI) ‐0.19 [‐0.33, ‐0.04]
2 Developmental delay 1 38 Risk Ratio (M‐H, Fixed, 95% CI) 0.77 [0.32, 1.87]
3 Hearing loss at 4 to 10 weeks after discharge 1 59 Risk Difference (M‐H, Fixed, 95% CI) ‐0.25 [‐0.48, ‐0.01]
4 Hearing loss at 2 years of age 1 38 Risk Difference (M‐H, Fixed, 95% CI) 0.04 [‐0.12, 0.21]
5 Seizures at any time 1 52 Risk Ratio (M‐H, Fixed, 95% CI) 1.85 [0.18, 19.19]
6 Seizures persisting after 5 days of treatment 1 52 Risk Ratio (M‐H, Fixed, 95% CI) 1.85 [0.18, 19.19]
7 Hydrocephalus 1 52 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.06, 14.03]