Skip to main content
. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Biomaterials. 2023 Feb 20;296:122065. doi: 10.1016/j.biomaterials.2023.122065

Fig. 7. Engineered OMVs as a versatile antigen display platform.

Fig. 7.

(A) SpyCatcher (SpC) and SnoopCatcher (SnC) are genetically introduced onto the surface of OMVs via fusion with cytolysin A (ClyA). Antigens labeled with SpyTag (SpT) or SnoopTag (SnT) can then be readily conjugated onto the surface of the OMVs. (B) Engineered OMVs expressing the MC38-related antigen Adpgk are able to significantly suppress tumor growth and improve survival in an MC38 tumor model. Adapted with permission [66]. Copyright 2020, Springer Nature.