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. 2023 Oct 2;2023(10):CD011806. doi: 10.1002/14651858.CD011806.pub2

Jing 2019.

Study characteristics
Methods Study design: RCT
Setting: China
Participants State of disease/disease type: unknown CD and UC
Inclusion criteria: confirmed diagnosis of IBD
Exclusion criteria: intestinal surgery, non‐steroidal drugs within past month, long‐term smoker, pregnancy, hepatic disease, renal disease, calcium or vitamin D supplementation
Age: mean: 41.9 years
Sex (male:female): 104:94
Number randomised: 99 (Group 1); 99 (Group 2)
Number analysed: 99 (Group 1); 99 (Group 2)
Interventions Group 1: vitamin D 400 IU/day
Group 2: no intervention
Outcomes Duration of follow‐up: 1 month
Outcomes
  • 25(OH)D

  • Diamine oxidase

  • D‐lactic acid

  • Endotoxin

  • Interleukin‐1β, interleukin‐6, CRP, TNF‐α

Notes Funding source: not stated
Conflicts of interest: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Reported as randomised, although method of randomisation was not reported.
Quote: "randomly divided".
Allocation concealment (selection bias) Unclear risk No information to assess allocation concealment.
Blinding of participants and personnel (performance bias)
All outcomes High risk Blinding was not reported.
Blinding of outcome assessment (detection bias)
All outcomes High risk Blinding was not reported.
Incomplete outcome data (attrition bias)
All outcomes Low risk No withdrawals.
Selective reporting (reporting bias) Unclear risk Outcomes reported per methods but no trial registration.
Other bias Unclear risk No baseline characteristics reported.