Skip to main content
. 2023 Oct 1;4(5):e370. doi: 10.1002/mco2.370

FIGURE 1.

FIGURE 1

Small cell lung carcinoma (SCLC) molecular subtypes defined by ASCL1, NEUROD1, POU2F3, and Vimentin (VIM). (A) Differential expression of ASCL1, NEUROD1, POU2F3, and VIM across NMF‐defined 4 clusters using SCLC RNA sequencing data from George et al. (B) Representative images of immunohistochemistry (IHC) staining in primary SCLC tumors. (C) The proportion of each dominant molecular subtype tumor (N = 145). (D) The proportion of different co‐expression conditions for ASCL1 (A) and NEUROD1 (N). (E) A case with dual‐high NEUROD1 and VIM expression not only in the same cell populations but in spatially distinct subpopulations.