Table 3.

Comparison of elevated laboratory values during 1 to 6 months after COVID-19 vs ORI among matched cohorts of pediatric patients with laboratory values measured during the acute period of infection (01/01/2020 – 12/31/2022)

n, 1–4 = 5513 n, 1–10 = 11,308	Age Group (years)	COVID-19 Cohort No.	ORI Cohort No.	HR (95% CI)
Elevated ASTa or ALTb	1–4	82	37	2.23 (1.50–3.27)
	1–10	144	56	2.59 (1.90–3.53)
Elevated TBil c	1–4	19	10	3.61 (1.35–9.66)
	1–10	39	10	4.17 (2.02–8.60)

Abbreviations: ORI, other respiratory infection; HR, hazard ratio; CI, confidence interval; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBil, total bilirubin; Inpt, inpatient. Cohorts matched on factors listed in Table 1. Patients with elevated labs from 0 to 1 months after respiratory illness are excluded from this analysis.

^aAST ≥110 units per liter

^bALT ≥100 units per liter

^cTBil ≥2 milligrams per deciliter