Table 1.
Variables | Short surviving group (228, 46.4%) | Long surviving group (n = 263, 53.6%) | P value |
---|---|---|---|
N (%) or median (IQR) | |||
Recipient | |||
Age, years | 52 (43–59) | 52 (43–59) | 1.00 |
Sex (F/M) | 74 (32.5)/154 (67.5) | 69 (26.2)/194 (73.8) | 0.14 |
Period of transplant | |||
1982–1991 | 35 (15.4) | 17 (6.5) | < 0.0001 |
1992–2001 | 104 (45.6) | 101 (38.4) | |
2002–2012 | 89 (39.0) | 145 (55.1) | |
Blood group | |||
O | 99 (43.4) | 104 (39.5) | |
A | 93 (40.8) | 106 (40.3) | 0.48 |
B | 30 (13.2) | 40 (15.2) | |
AB | 6 (2.6) | 13 (4.9) | |
Caucasian ethnicity | 225 (98.7) | 258 (98.1) | 0.73 |
UNOS status | |||
1 | 13 (5.7) | 12 (4.6) | |
2A | 59 (25.9) | 34 (12.9) | < 0.0001 |
2B | 150 (65.8) | 192 (73.0) | |
3 | 6 (2.6) | 25 (9.5) | |
HCC* | 72 (31.6) | 83 (31.6) | 1.00 |
HCV* | 110 (48.2) | 106 (40.3) | 0.08 |
HBV* | 62 (27.2) | 67 (25.5) | 0.68 |
+ HDV | 13 (5.7) | 14 (5.3) | 1.00 |
Alcohol* | 36 (15.8) | 60 (22.8) | 0.053 |
NASH or cryptogenic* | 8 (3.5) | 20 (7.6) | 0.054 |
Biliary cholangiopathies* | 14 (6.1) | 15 (5.7) | 0.85 |
Acute liver failure* | 13 (5.7) | 12 (4.6) | 0.68 |
Other diseases* | 28 (12.3) | 38 (14.4) | 0.51 |
Donor | |||
Age, years | 38 (23–55) | 38 (23–56) | 0.80 |
Sex (F/M) | 109 (47.8)/119 (52.2) | 96 (36.5)/167 (63.5) | 0.01 |
Blood group | |||
O | 120 (52.6) | 113 (43.0) | |
A | 81 (35.5) | 103 (39.2) | 0.10 |
B | 24 (10.5) | 39 (14.8) | |
AB | 3 (1.3) | 8 (3.0) | |
Donor-recipient blood iso-group | 23 (10.1) | 13 (4.9) | 0.04 |
Donor-recipient sex match | |||
F–M | 66 (28.9) | 66 (25.1) | |
F–F | 43 (18.9) | 30 (11.4) | 0.04 |
M–F | 31 (13.6) | 39 (14.8) | |
M–M | 88 (38.6) | 128 (48.7) | |
Transplantation | |||
Split liver | 0 (–) | 5 (1.9) | 0.06 |
Type of perfusion | |||
Collins | 15 (6.6) | 2 (0.8) | |
Belzer | 179 (78.5) | 392 (81.0) | 0.002 |
Celsior | 34 (14.9) | 48 (18.3) | |
Total ischemia time, min | 490 (433–604) | 460 (390–540) | < 0.0001 |
Type of caval reconstruction | |||
Caval replacement | 166 (72.8) | 171 (65.0) | 0.005 |
Piggyback | 40 (17.5) | 39 (14.8) | |
Piggyback LL | 22 (9.6) | 53 (20.2) |
N number, IQR interquartile ranges, F female, M male, UNOS united network for organ sharing, HCC hepatocellular carcinoma, HCV hepatitis C virus, HBV hepatitis B virus, HDV hepatitis D virus, NASH non-alcoholic steato-hepatitis, LL latero-lateral
*Some patients had multiple causes of hepatopathy requiring transplantation