Figure 3.

α-globin aggregates in red blood cell membranes of Hbb^th3/+ mice afer vamifeport treatment alone or in combination with repeated blood transfusions. (A) TAU gel electrophoresis of membrane-bound globins in red blood cells from Hbb^th3/+ and wild-type (WT) mice. Soluble α and b hemoglobin from wild-type red blood cells are shown for reference. (B) Quantification of the signal intensity of the TAU gel α bands by densitometry represented as a scatter plot of individual values (with mean and standard deviation).