Figure 5.
Leukocyte, neutrophil, lymphocyte, and monocyte counts in Hbbth3/+ mice afer vamifeport treatment alone or in combination with repeated blood transfusions. Representative scatter plots of individual values (with mean and standard deviation) showing the effects of transfusion, vehicle, and vamifeport treatment at the end of the study on counts of: (A) leukocytes, (B) neutrophils, (C) lymphocytes, (D) monocytes. WT: wild-type. Analysis was performed by using one-way analysis of variance with Dunnett’s multiple comparison test. Significant differences compared with the Hbbth3/+ vehicle non-transfused group (black) are indicated as: *P<0.05, **P<0.01, and ***P<0.001. There were no significant differences between any other treatment group compared with the vehicle-transfused group, for any of these parameters.