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Assumptions for Donner and Klar’s cluster-randomized power calculation using a mixed model test for two proportions in a 2-level hierarchical design. An intraclass correlation coefficient of 0.025 is based on ED patients in the New York Sepsis Clinical Database
| Compliant ED patients with the bundle | Pre-intervention mortality, % | Intervention period | Post-intervention mortality, % | Difference | Difference in difference |
|---|---|---|---|---|---|
| 3-h arm | 19.1 | 18.9 | 0.2% | 2.7% | |
| 1-h arm | 19.1 | 16.2 | 2.9% |
