Table 2.
Biochemical parameters, insulin resistance and thyroid function tests before and after levothyroxine treatment
| Parameters | Before | After | p* | |
|---|---|---|---|---|
| Anthropometric | Weight (Kg) | 73.45± 9.33 | 68.25±7.77 | 0.001 |
| BMI (kg/m 2 ) | 27.13±4.27 | 26.81±4.18 | 0.028 | |
| Biochemical | Cholesterol (mg/dl) | 199.79±37.61 | 178.10±32.25 | <0.001 |
| Triglyceride (mg/dl) | 160.41±71.86 | 146±61.11 | 0.012 | |
| HDL-C (mg/dl) | 44.31±10.56 | 44.31±10.59 | 0.954 | |
| LDL-C (mg/dl) | 123.54±30.7 | 107.08±26.98 | <0.001 | |
| IR | FBG (mg/dl) | 91.95±13.17 | 92.69±13.38 | 0.134 |
| Fasting insulin (mIU/l) | 8.91±3.92 | 8.05±2.65 | <0.001 | |
| HOMA-IR | 2.07±1.56 | 2.09±1.46 | 0.451 | |
| QUICKI | 0.356±0.36 | 0.355±0.035 | 0.934 | |
| TFT | TSH (µIU/ml) | 47.45±3.4 | 2.22±1.84 | <0.001 |
| FT4 (ng/dl) | 0.8±0.19 | 1.20±0.44 | <0.001 | |
Data are presented as mean ± standard division. P < 0.05 was considered as statistically significant. BMI, body mass index; HDL, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FBG, fasting blood glucose; HOMA-IR, homeostatic model assessment for insulin resistance; QUICKI, quantitative insulin sensitivity check index; IR, insulin resistance; TFT, thyroid function test
*Paired samples t-test
P < 0.05 is statistically significant