Table 1.
Characteristics of the Population with Asthma
Total (n = 142) |
Vitamin D | P | ||
---|---|---|---|---|
<20 ng/mL (n = 94) |
≥20 ng/mL (n = 48) |
|||
Age (years), mean ± SD | 34.6 ± 10.4 | 36.0 ± 10.2 | 31.8 ± 10.3 | .024 |
Sex, female, n (%) | 106 (74.6) | 69 (73.4) | 37 (77.1) | .634 |
Current smoking, n (%) | 8 (5.6) | 6 (6.4) | 2 (4.2) | .717 |
Alcohol consumption, n (%) | 33 (23.2) | 18 (19.1) | 15 (31.3) | .106 |
Atopic comorbidity, n (%) | ||||
Allergic rhinitis | 117 (82.4) | 74 (78.7) | 43 (89.6) | .108 |
Food allergy | 27 (19.0) | 18 (19.1) | 9 (18.8) | .954 |
Atopic dermatitis | 13 (9.2) | 8 (8.5) | 5 (10.4) | .709 |
Urticaria | 7 (4.9) | 2 (2.1) | 5 (10.4) | .044 |
BMI (kg/m2), mean ± SD | 29.1 ± 6.2 | 29.8 ± 6.7 | 27.9 ± 4.9 | .078 |
Hospitalization in the previous year, n (%) | 52 (36.6) | 32 (34.0) | 20 (41.7) | .372 |
ACT, points | ||||
Mean ± SD | 15.2 ± 5.4 | 14.6 ± 5.4 | 16.2 ± 5.3 | .103 |
≥20, n (%) | 40 (28.2) | 24 (25.5) | 16 (33.3) | .328 |
Allergic sensitization, n (%) | ||||
Mites | 94 (66.2) | 60 (63.8) | 34 (70.8) | .404 |
Cockroaches | 70 (49.3) | 45 (47.9) | 25 (52.1) | .635 |
Trees | 67 (47.2) | 43 (45.7) | 24 (50.0) | .631 |
Epithelia | 57 (40.1) | 37 (39.4) | 20 (41.7) | .791 |
Weeds | 60 (42.3) | 36 (38.3) | 24 (50.0) | .182 |
Grass | 43 (30.3) | 29 (30.9) | 14 (29.2) | .836 |
Fungi | 18 (12.7) | 12 (12.8) | 6 (12.5) | .964 |
Respiratory function, mean ± SD | ||||
% predicted baseline | ||||
FVC | 87.9 ± 18.3 | 85.1 ± 18.9 | 93.4 ± 16.0 | .011 |
FEV1 | 71.2 ± 19.2 | 68.8 ± 20.55 | 75.9 ± 15.4 | .039 |
FEV1/FVC | 67.1 ± 10.3 | 66.7 ± 11.2 | 67.9 ± 8.1 | .493 |
Total serum IgE, IU/mL | ||||
Median (P25-P75) | 211 (74-502) | 204 (67-524) | 224 (82-501) | .626 |
IgE ≥100, n (%) | 95 (66.9) | 61 (64.9) | 34 (70.8) | .477 |
Vitamin D, ng/mL | ||||
Mean ± SD | 18.4 ± 8.1 | 14.2 ± 3.7 | 26.5 ± 8.2 | <.0001 |
≥20, n (%) | 48 (33.8) | N/A | N/A | N/A |
Eosinophils, cells/µL | ||||
Mean ± SD | 418.1 ± 344.5 | 464 ± 378 | 328 ± 247 | .025 |
Median (P25-P75) | 340 (205-580) | 359 (227-602) | 240 (145-477) | .023 |
ACT, asthma control test; BMI, body mass index; FEV1, forced expiratory volume; FVC, forced vital capacity; IgE, immunoglobulin E; N/A, not applicable; P25-P75, percentile 25-percentile 75.