Table 1.
Study population and clinical assessment of hyperOH and OH
| Parameters | HyperOH | OH | Significance |
|---|---|---|---|
| Age (years) | 70 ± 10 | 70 ± 9 | p = 0.97 |
| Sex (% male) | 56% | 64% | p = 0.46 |
| BMI (kg/m2) | 24.3 ± 3.9 | 27.9 ± 4.7 | p = 0.03 |
| SBP supine (mmHg) | 149 ± 25 | 153 ± 27 | p = 0.55 |
| DBP supine (mmHg) | 79 ± 11 | 83 ± 13 | p = 0.11 |
| HR supine (bpm) | 73 ± 13 | 65 ± 11 | p = 0.006* |
| NE supine (pg/mL) | 420±179 | 116 ± 84 | p< 0.0005*** |
| SBP upright (mmHg) | 115 ± 29 | 94 ± 17 | p = 0.003** |
| DBP upright (mmHg) | 70 ± 15 | 62 ± 11 | p = 0.02* |
| HR upright (bpm) | 82 ± 15 | 78 ± 13 | p = 0.28 |
| NE upright (pg/mL) | 938 ± 305 | 209 ±159 | p< 0.0005*** |
| ΔSBP | 34 ± 14 | 59 ± 9 | p< 0.0005*** |
| ΔDBP | 9 ± 4 | 21 ± 2 | p = 0.003** |
| ΔHR | 9 ± 2 | 13 ± 3 | p = 0.15 |
| ΔHR/ΔSBP | 0.33 | 0.22 | p = 0.25 |
| ΔNE | 518 ± 126 | 94 ± 75 | p< 0.0005*** |
| VM Ratio | 1.2 ± 0.14 | 1.1 ± 0.12 | p = 0.08 |
| PRT (seconds) | 16.5 ± 9 | 32 ± 17 | p< 0.001** |
Values are means ± standard deviations. BMI = body mass index. SBP = systolic blood pressure. DBP = diastolic blood pressure. HR = heart rate. NE = norepinephrine. VM = Valsalva Maneuver. PRT = pressure recovery time.