Skip to main content
. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Transfusion. 2023 Apr 18;63(Suppl 4):S8–S18. doi: 10.1111/trf.17360

TABLE 1.

Estimated numbers of whole blood and RBC units collected, transfused, and outdated in 2021 and 2019 (expressed in thousands) in the United States, as reported to the National Blood Collection and Utilization Survey.

Blood
centers
Hospitals Combined
totals
95% CI 2019
totalsa
% change
2021–2019
Collections
Whole blood units
 Allogeneic, nondirected 9490 351 9842 (9491–10,193) 9777 0.7%
 Autologous 2 1 3b (2–3)c 5 −40.0%
 Directed 4 5 9 (6–13) 9 0.0%
Apheresis RBC unitsd 1922 9 1931 (1771–2090) 1800 7.3%
Total supply 11,419 366 11,784 (11,392–12,177) 11,590 1.7%
Rejected on testing 117 4 121 (108–133) 103 17.5%
Rejected for other reasonse 610 20 630 (551–709) 608 3.6%
Total available supply 10,692 342 11,033 (10,647–11,420) 10,879 1.4%
Transfusions
 Allogeneic, nondirected 10,752 (10,346–11,159) 10,834 −0.8%
 Autologous 2f (1–2)g 9 −77.8%
 Directed 10 (2–18) 9 11.1%
 Total transfusions 10,764 (10,357–11,171) 10,852 −0.8%
Outdated whole blood or RBCs 159 146 305 (254–356) 349 −12.6%
a

2019 totals were obtained from the 2019 NBCUS report.5

b

Estimate is rounded from 2649 to 3000.

c

Lower bound of the 95% CI is rounded from 2219 to 2000; upper bound of the 95% CI is rounded from 3080 to 3000.

d

Apheresis RBC units include allogeneic, autologous, directed, and concurrent collections.

e

Units rejected for other reasons do not include outdated units.

f

Estimate is rounded from 1615 to 2000.

g

Lower bound of the 95% CI is rounded from 810 to 1000; upper bound of the 95% CI is rounded from 2420 to 2000.