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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Transfusion. 2023 Apr 18;63(Suppl 4):S8–S18. doi: 10.1111/trf.17360

TABLE 4.

Estimated numbers of platelets, plasma, and cryoprecipitated AHF units distributed, transfused, and outdated in 2021 and 2019 (expressed in thousands) in the United States, as reported to the National Blood Collection and Utilization Survey.

Blood
centers
Hospitals Combined
totals
95% CI 2019
totalsa
% change
2021–2019
Distributed
Apheresis platelets 2265 157 2422 (2298–2545) 2359 2.7%
Whole blood-derived plateletsb 62 45 107 (38–175) 149 −28.2%
Total platelets 2327 202 2528 (2372–2684) 2508 0.8%
Pathogen-reduced apheresis platelets 916 35 951 (884–1017) n/ac
Total plasmad 2985 129 3114 (2929–3298) 2679 16.2%
Cryoprecipitated AHFe 2306 143 2449 (2234–2664) 2304 6.3%
Blood center outdatesf 179 35 214 (161–267) 229 −6.6%
Transfused
Apheresis platelets 2091 (1919–2264) 1996 4.8%
Whole blood-derived plateletsb 80 (47–112) 243 −67.1%
Total platelets (includes directed units) 2175 (1997–2353) 2243 −3.0%
Pathogen-reduced apheresis platelets 843 (712–974) n/ac
Total plasmad 2215 (2084–2347) 2185 1.4%
Cryoprecipitated AHFe 1248 (1075–1421) 1184 5.4%
Hospital outdatesg 523 (468–578) 500 4.6%
a

2019 totals were obtained from the 2019 NBCUS report.5

b

Whole blood-derived platelets are expressed as apheresis equivalents.

c

Estimate not available for 2019.

d

Excludes COVID-19 convalescent plasma.

e

Cryoprecipitated AHF is expressed as individual unit equivalents.

f

Blood center outdates are units that were outdated at non-hospital and hospital-based blood centers.

g

Hospital outdates are units that were outdated at transfusing hospitals.