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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: J Neurochem. 2023 Jul 31;167(1):52–75. doi: 10.1111/jnc.15908

Table 3.

qPCR results with full statistical report. The table includes raw Ct values for fifty-five target genes and for three housekeeping genes (Hars2, Srbd1, and Srp68, highlighted in yellow columns), calculation of △△CT values and fold changes. Mean fold changes, standard deviations (SD), and standard error of mean (SEM) are highlighted in green rows. n=5 independent experiments, each with 4 samples (A, AN, AE, AEN).

housekeeping genes
Triplicate mean Ct HARS2 SRBD1 SRP68 ADCY1 ALDOC APPL2 AQP4 ATP1B1 CCND1 CCND2 CDK1 CLCN5 CLDN10 DAPP1 eGFP EMC7 EPHB1 EPHB2 FABP7 FAM43A FZD1 FZD10 GJA1 GLI1 GLUL GPC4 GSN HES5 HEY1 HEY2 KALRN KCNJ10 MKI67 NFIA NRP2 OLIG2 PDLIM1 PLD2 S100B S1PR1 SEMA3C SHH SLC1A2 SLC1A3 SLC1A4 SLC6A11 SLC7A11 SMIM12 SOX9 SPARC SPARCL1 SYT11 THBS1 TLN2 TNF TNFRSF19 VIM ZBTB20
A_G1 11.579 12.689533 10.632867 12.912 8.4878333 11.6816 8.4048 7.8249 7.4518333 7.8992 10.800433 13.607033 15.3486 11.807367 19.9026 9.4475667 15.281267 9.8918667 5.8906667 11.1743 13.121 15.4508 9.4114667 13.694867 10.1352 7.1642667 9.9924333 14.675833 11.054167 14.1181 15.336133 7.6148667 11.7028 9.2911 13.331967 11.564067 11.9488 11.0105 12.946133 11.009967 10.910667 11.2075 10.932767 7.4944 11.617733 15.7903 16.5152333 19.354167 8.6986667 5.4468333 9.5356 8.1963667 7.5312333 10.665867 10.6779 13.561933 4.7531 10.509467
A_G2 11.4825 12.4694 10.3724 12.9756 8.1165667 11.645267 8.2525 7.6151 7.5714667 8.0035333 10.4604 13.731367 14.7203 11.388133 18.966033 9.2051 14.8293 9.7568667 5.7257667 11.033033 12.744633 15.3936 8.9161667 13.551733 9.9743333 6.9075333 9.8411667 15.666567 10.7587 13.943533 15.4075 7.5178667 11.7191 9.0542333 13.676433 11.404833 11.634067 10.866467 12.557267 10.773 10.803533 11.069467 10.8708 7.1223667 11.261033 15.283433 16.767 19.580933 8.5718667 5.3054 9.3577 7.7308 7.4609 10.6466 10.991633 13.386867 4.4952333 10.577167
A_G3 11.657567 12.498433 10.496 13.220133 8.1112 11.613433 8.2024667 7.6092667 7.4972667 7.841 10.8158 13.780467 14.782267 11.444633 18.720433 9.1362667 14.9517 9.7789 5.6789333 11.2085 12.922 15.5271 8.9906 13.521967 9.9291333 6.9905 9.6957667 17.2793 10.7577 14.074967 15.511533 7.3093333 12.017733 9.0275 13.0834 11.327067 11.868567 10.825867 12.395767 10.682067 10.675667 11.415867 10.4744 7.154 11.265467 15.079733 16.4091333 20.007367 8.4933333 5.1854667 9.2735333 7.7983667 7.477 10.6222 11.703367 13.375333 4.6026333 10.495533
A_G4 11.543567 12.585867 10.344633 13.294667 8.0132 11.603467 8.0499333 7.5199333 7.3771 7.9236333 10.47 13.891167 15.165 11.471367 19.916033 9.0639 14.957867 9.6661667 6.0262333 10.881733 12.8114 15.8638 8.9933 13.345767 9.8886333 6.757 9.5652667 19.007267 10.699 14.4345 15.500033 7.3453333 12.149233 9.1577333 13.352433 12.049133 11.7129 10.829433 13.113933 10.7646 10.554467 11.374 11.045533 7.3381 11.350633 15.766633 16.4478667 19.685533 8.3974333 5.1451333 9.4956667 7.8941 7.2432333 10.628067 11.960633 13.522767 4.5749333 10.809467
A_G5 12.102767 13.132133 11.035033 13.503667 8.3408 12.208133 8.7431333 8.4738667 8.2982333 8.6158333 11.3041 14.623633 14.8948 12.362667 18.9057 9.8087333 14.736133 10.468433 6.4991667 11.806133 13.0922 15.601533 9.8186333 14.206133 10.514933 7.5655333 10.657433 16.353633 11.327833 14.887467 15.776233 8.1488333 12.4349 10.033333 14.069467 11.9734 12.3345 11.561033 13.903733 11.8927 11.5754 13.435633 10.9352 7.8528667 11.775833 16.440267 17.6587 21.102733 9.4282667 5.8915667 9.9346333 8.4866 8.0540667 11.204533 13.0706 14.199133 4.9620333 11.223267
Mean 11.67308 12.675073 10.576187 13.181213 8.21392 11.75038 8.3305667 7.8086133 7.63918 8.05664 10.770147 13.926733 14.982193 11.694833 19.28216 9.3323133 14.951253 9.9124467 5.9641533 11.22074 12.938247 15.567367 9.2260333 13.664093 10.088447 7.0769667 9.9504133 16.59652 10.91948 14.291713 15.506287 7.5872467 12.004753 9.31278 13.50274 11.6637 11.899767 11.01866 12.983367 11.024467 10.903947 11.700493 10.85174 7.3923467 11.45414 15.672073 16.7595867 19.946147 8.7179133 5.39488 9.5194267 8.0212467 7.5532867 10.753453 11.680827 13.609207 4.6775867 10.72298
SD 0.2484033 0.2695246 0.2807707 0.24141 0.1945794 0.2577089 0.2631449 0.388378 0.3751201 0.3180001 0.3442886 0.4027111 0.2663966 0.4078196 0.5796413 0.3028707 0.2062171 0.321029 0.3292689 0.3518349 0.1665387 0.1833331 0.3844383 0.3274565 0.2561273 0.3101941 0.4262513 1.6500555 0.2671738 0.3787018 0.1670694 0.3379031 0.307751 0.4159139 0.3804439 0.3296717 0.2728949 0.3123997 0.5899881 0.5005106 0.3985052 0.9797395 0.2201338 0.2979658 0.23122 0.5279555 0.52157339 0.6879646 0.4121424 0.301509 0.2548734 0.315207 0.3007304 0.2527407 0.9342268 0.3397984 0.1844049 0.3067361
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.1110893 0.1205351 0.1255645 0.1079619 0.0870186 0.1152509 0.117682 0.1736879 0.1677588 0.142214 0.1539706 0.1800979 0.1191362 0.1823825 0.2592235 0.1354479 0.0922231 0.1435685 0.1472535 0.1573453 0.0744784 0.0819891 0.171926 0.146443 0.1145436 0.138723 0.1906254 0.7379272 0.1194838 0.1693606 0.0747157 0.1511148 0.1376304 0.1860024 0.1701397 0.1474337 0.1220423 0.1397094 0.2638507 0.2238351 0.1782169 0.4381528 0.0984468 0.1332544 0.1034047 0.2361089 0.23325471 0.3076671 0.1843157 0.1348389 0.1139828 0.1409648 0.1344907 0.1130291 0.4177989 0.1519625 0.0824684 0.1371766
AN_G1 11.340067 12.2161 10.3718 13.739267 6.7452333 10.8474 7.0579333 7.036 8.4655667 8.2855667 11.8638 14.416867 12.937633 10.693967 18.2123 8.7978333 12.527667 10.171967 5.6588667 11.457433 11.354567 13.137067 7.6547 12.649467 8.4943333 7.5134333 9.5910667 12.057633 9.9583667 12.0371 13.8229 6.8085333 13.039233 8.7416 13.1477 9.6403667 11.9162 9.956 9.8854 9.7110333 11.2121 13.454667 8.8794333 6.2241667 10.551567 10.987867 14.9864 19.7624 8.0228 5.1556 7.5377333 7.1497 7.8466333 10.804267 12.528833 11.019 4.8791 9.2164
AN_G2 12.162067 13.088767 11.063733 14.786533 7.5789333 11.864133 8.1242333 7.8736667 9.1505333 9.2722 11.852033 15.026333 14.017267 11.7556 18.5142 9.8033 14.845033 11.0714 6.7333 12.677067 12.565667 14.5732 8.4046667 14.000033 10.202767 8.1797667 10.260267 15.499 10.863067 13.397467 15.9004 7.8457 13.4624 9.6559667 14.318567 11.373367 12.897267 11.0812 11.347867 10.573 12.090033 13.8577 10.321667 7.2153667 11.362633 13.639633 16.9781 20.5364 9.0707333 5.8747667 8.8898667 8.1569 8.8791667 11.828433 13.694533 12.193133 5.3674333 10.779867
AN_G3 11.258367 12.0614 10.244533 13.7933 6.9007 10.9379 7.1492667 6.8803333 8.1633 8.0562333 11.228633 14.2723 13.213233 10.756767 18.0089 8.8273333 13.6522 9.9274667 5.8455 11.863867 11.4955 13.374367 7.5735333 12.835 9.2956 7.1236 9.3748333 14.793133 9.8510333 12.795533 14.754033 6.5841 12.4915 8.5865333 13.1071 10.877167 11.774867 10.2062 10.6308 9.5782 10.732467 12.790233 9.1161667 6.2067 10.3691 12.659467 15.5735333 18.6643 8.0274 4.9283333 7.9401 7.2259 7.6284 10.666567 12.703933 11.201633 4.6071333 9.2124333
AN_G4 12.2048 13.192433 11.144867 14.728133 7.4118333 11.937533 8.0448333 7.6165333 8.9448 8.8109667 11.933733 15.3149 14.253833 11.6509 19.310667 9.6116667 14.2204 10.6792 6.6986667 12.349733 12.4837 14.4528 8.4475 13.447267 9.6330667 7.7644667 9.9861667 15.8969 10.781233 13.828633 15.524833 7.3348333 13.862633 9.3511 14.118133 12.327633 12.865533 11.0035 12.076967 10.392233 11.424733 14.035933 10.330433 7.2529333 11.509267 14.2528 16.3472333 20.272833 8.6962667 5.4715333 8.8478667 8.1894 8.4596333 11.369167 13.459867 12.051033 5.4052333 10.652167
AN_G5 12.2657 13.598067 11.529067 14.604233 8.0345 12.5001 8.5523333 8.2469333 9.2451 9.1388667 11.969233 15.624267 14.279667 12.3493 18.556767 10.083867 14.204767 11.0658 6.8025667 12.2157 12.712467 14.673933 9.1596 13.964267 10.258433 7.8097333 10.6567 16.883267 11.334067 14.3792 15.887267 7.8253 13.319067 9.8361 14.946633 12.5171 12.757433 11.4603 12.9053 11.2644 11.747667 14.833767 10.836233 7.7477333 11.929867 15.356733 17.5731 20.494233 9.3629667 5.9451333 9.6369333 8.6565333 8.6009667 11.641567 15.138867 12.8902 5.6949667 11.455267
Mean 11.8462 12.831353 10.8708 14.330293 7.33424 11.617413 7.78572 7.5306933 8.79386 8.7127667 11.769487 14.930933 13.740327 11.441307 18.520567 9.4248 13.890013 10.583167 6.34778 12.11276 12.12238 14.042273 8.248 13.379207 9.57684 7.6782 9.9738067 15.025987 10.557553 13.287587 15.177887 7.2796933 13.234967 9.23426 13.927627 11.347127 12.44226 10.74144 11.369267 10.303773 11.4414 13.79446 9.8967867 6.92938 11.144487 13.3793 16.2916733 19.946033 8.6360333 5.4750733 8.5705 7.8756867 8.28296 11.262 13.505207 11.871 5.1907733 10.263227
SD 0.5015139 0.6625433 0.5447159 0.5194105 0.5222895 0.7066014 0.6527199 0.5713337 0.4634109 0.5286081 0.3062299 0.577777 0.6231806 0.7060938 0.4955906 0.5836531 0.8707514 0.5195087 0.5489683 0.4681335 0.6437727 0.7271362 0.6523552 0.6247068 0.7263663 0.3908457 0.5132773 1.8232569 0.633352 0.9086058 0.8889963 0.5759628 0.5108372 0.5513536 0.7919992 1.1688468 0.5494722 0.6332989 1.1840491 0.6857312 0.5171961 0.752728 0.8508096 0.6847937 0.6614856 1.6566632 1.04112755 0.7798102 0.6057049 0.4420723 0.8336994 0.6588812 0.5259833 0.5100154 1.0370739 0.7663071 0.438517 1.0048835
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.2242839 0.2962984 0.2436044 0.2322874 0.233575 0.3160018 0.2919052 0.2555082 0.2072437 0.2364007 0.1369502 0.2583897 0.2786949 0.3157747 0.2216348 0.2610176 0.3894119 0.2323313 0.2455061 0.2093557 0.2879039 0.3251852 0.2917421 0.2793774 0.3248409 0.1747915 0.2295446 0.8153853 0.2832436 0.4063409 0.3975713 0.2575784 0.2284533 0.2465728 0.3541928 0.5227242 0.2457314 0.2832199 0.5295228 0.3066683 0.2312971 0.3366302 0.3804936 0.306249 0.2958254 0.7408823 0.4656064 0.3487417 0.2708795 0.1977007 0.3728417 0.2946606 0.2352269 0.2280858 0.4637935 0.342703 0.1961108 0.4493976
AE_G1 11.9896 12.9426 10.796333 14.8048 6.6187 11.694933 7.0299 8.0402333 9.0651 8.3194667 11.1695 13.727967 13.354933 11.599033 15.319133 9.4110667 11.728833 12.4612 4.4984 11.8527 13.669333 13.459633 9.1156333 19.113267 8.8897333 9.7416667 9.5018333 12.288233 10.797833 12.1481 13.287033 8.6962333 11.908167 9.5903333 12.565267 12.0053 12.655167 10.747833 12.447733 9.6479333 14.3682 18.3739 8.6503667 6.5448667 10.995867 11.107533 11.3877 20.551433 8.8584 6.2179 7.5306667 7.2485333 11.0152 12.180367 11.400067 13.052933 5.2466 11.225233
AE_G2 11.079033 11.938333 10.084867 13.831767 6.0221667 11.0711 6.3990333 7.4522333 8.1575 7.4113 10.152467 12.979133 12.949167 10.721167 14.159367 8.5902667 10.940833 11.5908 3.7367 11.077633 13.008367 12.8108 8.2455333 17.692133 8.2778667 8.7997333 8.6964 12.082367 9.9956333 11.3796 12.433 7.9723 10.835233 8.6379333 11.7518 10.6804 12.2856 9.9703 11.605467 8.9658 13.3903 16.857867 8.3298667 5.8122667 10.2442 10.374467 11.2126 19.3108 8.1303333 5.3026 7.0818333 6.4491667 9.7763 11.3124 12.041367 12.189467 4.6530667 10.314267
AE_G3 11.495 12.354233 10.3557 14.387733 5.9564 11.172233 6.5798333 7.8843667 8.8964 7.9738 11.1064 13.2162 12.595533 11.032733 13.805033 8.9012667 11.1699 12.420733 4.2388667 11.377367 13.1563 12.810267 8.6413333 19.941967 8.4963333 9.8204667 9.1460667 12.505067 10.219067 11.785833 12.798233 8.4824 11.6773 9.3969 11.8334 11.1459 11.646767 10.286933 12.0825 9.3529333 14.312333 19.534 7.7451667 5.9411 10.4665 10.419067 10.9179 19.8303 8.6951667 5.8778 6.9361333 6.6995333 11.280533 12.162833 12.892667 12.494133 4.7721 10.6009
AE_G4 11.851133 12.760933 10.6809 15.4119 6.6416333 11.668433 7.1106 8.2684333 9.2771333 8.4904667 11.443467 13.6594 13.2646 11.2117 15.1631 9.3853 11.765533 12.510767 4.5943 11.5183 13.6342 13.324967 8.9342667 18.314733 8.9143333 9.8460333 9.5150333 13.561667 10.725867 12.3613 13.770933 8.9401 12.663167 9.7421333 12.174967 12.201567 12.073167 10.750667 13.309967 9.853 14.092367 18.287267 8.8086 6.4244 11.249333 11.971467 11.7382667 20.155567 8.9456 6.0528667 7.894 7.2716333 11.156867 12.750933 12.6712 13.223433 4.9471667 11.246
AE_G5 11.3918 12.742633 11.303 14.9016 6.3007667 11.5315 7.2375667 8.2883667 9.1991667 8.7099333 11.2252 13.522833 12.077367 11.541667 14.527133 9.4835333 11.2858 12.709733 4.8201 10.861667 12.765067 13.320033 9.0215667 20.440533 8.8374333 10.2157 9.4014667 12.693467 10.8599 12.768167 13.3508 8.8381 11.557067 9.7083 11.980533 11.076067 11.6938 10.668767 11.997367 9.8931333 14.591933 20.244533 8.2175667 6.4292333 11.198033 10.870233 11.0552333 19.686 8.8745333 6.2750667 7.4566 7.2193 11.499167 12.4472 13.018733 12.846567 5.2481333 11.189667
Mean 11.561313 12.547747 10.64416 14.66756 6.3079333 11.42764 6.8713867 7.9867267 8.91906 8.1809933 11.019407 13.421107 12.84832 11.22126 14.594753 9.1542867 11.37818 12.338647 4.3776733 11.337533 13.246653 13.14514 8.7916667 19.100527 8.68314 9.68472 9.25216 12.62616 10.51966 12.0886 13.128 8.5858267 11.728187 9.41512 12.061193 11.421847 12.0709 10.4849 12.288607 9.54256 14.151027 18.659513 8.3503133 6.2303733 10.830787 10.948553 11.26234 19.90682 8.7008067 5.9452467 7.3798467 6.9776333 10.945613 12.170747 12.404807 12.761307 4.9734133 10.915213
SD 0.3650861 0.4025452 0.4622215 0.5925591 0.3214114 0.2883433 0.362132 0.3425525 0.4495807 0.507465 0.5009637 0.3156827 0.5240196 0.3643831 0.6452782 0.3904626 0.3592308 0.4325398 0.4145351 0.3852457 0.3955126 0.3105458 0.3532014 1.1296951 0.2824362 0.5274546 0.3441862 0.5710237 0.3875 0.5324625 0.5196311 0.3835535 0.6587521 0.4549569 0.324482 0.650737 0.4211776 0.3455346 0.6446857 0.3869718 0.4609037 1.2983729 0.4136124 0.3296172 0.4511351 0.649556 0.31867988 0.4709718 0.3318177 0.391231 0.3803567 0.3790917 0.6773767 0.5361803 0.6759197 0.4196007 0.2710812 0.4303448
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.1632715 0.1800237 0.2067117 0.2650005 0.1437396 0.128951 0.1619503 0.1531942 0.2010586 0.2269453 0.2240378 0.1411776 0.2343487 0.1629571 0.2885772 0.1746202 0.1606529 0.1934377 0.1853857 0.1722871 0.1768786 0.1388803 0.1579565 0.505215 0.1263093 0.2358848 0.1539248 0.2553695 0.1732953 0.2381244 0.2323861 0.1715303 0.2946029 0.2034629 0.1451128 0.2910184 0.1883563 0.1545278 0.2883122 0.173059 0.2061224 0.58065 0.1849731 0.1474093 0.2017538 0.2904903 0.14251798 0.210625 0.1483934 0.1749638 0.1701007 0.169535 0.3029321 0.2397871 0.3022805 0.1876511 0.1212312 0.192456
AEN_G1 12.989867 14.1618 12.184833 17.6474 7.4669667 11.753067 8.8193667 9.6138333 12.113067 11.462633 15.256433 15.387667 12.024633 12.056533 15.098233 11.022067 13.147833 15.239667 7.4937333 12.9409 13.691533 14.836933 8.9574 15.339967 9.1646333 12.000767 10.156967 12.880767 12.5596 13.579733 15.381533 9.9716333 17.0373 10.8421 13.6881 12.508533 14.108 11.089033 12.095533 10.476367 16.342567 23.7607 8.2019667 7.3051667 11.688767 11.243533 11.6517667 21.277733 9.5414333 7.1863 7.7601667 8.1919333 12.7568 14.626333 13.9658 12.286533 7.1744667 11.1961
AEN_G2 11.9364 12.7655 10.840733 16.006467 5.9798 10.910967 7.0704333 7.8112 10.1082 9.3573667 12.907467 14.199867 11.4423 10.827067 13.1792 9.4247333 11.5698 13.245767 5.4605667 11.894667 12.9256 13.596567 7.6389333 14.4656 8.2069667 9.9540667 8.7218667 12.232833 10.820367 11.8826 13.737467 8.2468667 13.912 9.0464 12.5236 11.860567 13.587567 10.044133 11.117867 8.9000667 14.368 20.754733 7.4005667 5.9837667 10.329733 10.165133 10.6250333 19.781367 8.1109667 5.6159333 6.7194667 6.7516 11.301267 12.8117 13.1425 11.214333 5.5886667 10.455933
AEN_G3 11.8241 13.245767 10.7493 15.4111 5.5614667 11.000233 6.5519 7.5416333 9.9750667 8.805 12.980233 14.016633 11.172 10.903 12.676733 9.0898667 11.187267 13.039433 4.6716 12.0489 12.8023 12.6417 7.6545 15.143367 8.0288 9.8229 8.6932 12.153333 10.3221 11.5785 13.520833 7.8905333 14.6998 9.0371 12.369133 11.7463 12.946467 9.9424 11.354567 8.7419333 14.516833 21.6864 6.7447 5.6467 10.065033 9.7771 9.80996667 19.8751 8.1184 5.5747 6.2166 6.4746667 11.5793 12.772067 13.051367 11.056333 5.2675667 10.1847
AEN_G4 12.133333 13.095667 11.068933 16.5516 6.1255333 11.335633 7.6346 8.1608667 10.5775 9.5750667 13.394033 14.339233 11.475233 11.0686 13.345567 9.5602 11.742 13.182267 5.7083667 11.759333 13.136767 13.752433 7.9951333 14.6934 8.373 10.320067 8.9708 12.822233 11.246 12.504133 14.264967 8.4399333 14.921333 9.3453667 12.757633 11.911733 13.276 10.334333 12.027433 9.1154667 14.188333 22.7563 7.2922 6.2458 10.847967 10.973833 10.4874667 20.702333 8.331 5.7574667 7.2205333 6.9475 11.975433 13.4258 12.812467 11.249033 5.7717667 10.5385
AEN_G5 12.274367 13.7451 11.957833 16.813 6.4232667 11.9489 8.4101667 8.7572667 11.111833 10.229933 14.505467 15.235933 11.480167 12.086667 13.6528 10.112767 12.027333 13.918467 6.0122 12.471833 13.037233 13.885767 8.7718 14.638267 9.1423667 11.0585 9.8768 13.582867 11.936867 13.313533 14.753567 8.5327333 15.0294 9.9743 14.047133 11.975367 13.243433 10.976333 12.007167 9.872 15.1784 22.827867 7.6742333 6.6136333 11.395667 10.742933 10.7366667 21.229 9.0657 6.3557 7.4862 7.5163333 12.695333 13.716667 14.371833 11.7717 6.5975333 11.083267
Mean 12.231613 13.402767 11.360327 16.485913 6.3114067 11.38976 7.6972933 8.37696 10.777133 9.886 13.808727 14.635867 11.518867 11.388373 13.590507 9.8419267 11.934847 13.72512 5.8692933 12.223127 13.118687 13.74268 8.2035533 14.85612 8.5831533 10.63126 9.2839267 12.734407 11.376987 12.5717 14.331673 8.61634 15.119967 9.6490533 13.07712 12.0005 13.432293 10.477247 11.720513 9.4211667 14.918827 22.3572 7.4627333 6.3590133 10.865433 10.580507 10.66218 20.573107 8.6335 6.09802 7.0805933 7.1764067 12.061627 13.470513 13.468793 11.515587 6.08 10.6917
SD 0.4581629 0.551904 0.664279 0.8434223 0.7167206 0.455119 0.932208 0.8275023 0.8699681 1.0184248 1.031012 0.6298453 0.3103951 0.6298728 0.9139571 0.7558272 0.7431714 0.9118484 1.0352116 0.4822859 0.3436924 0.7828578 0.6234748 0.3684637 0.5347492 0.9037368 0.6849481 0.5784119 0.8876668 0.8706776 0.7574947 0.796592 1.1575349 0.7679598 0.7456413 0.2961453 0.4406849 0.5285458 0.4511402 0.7319586 0.8793525 1.1585003 0.5337875 0.6366033 0.6868306 0.599727 0.66011405 0.7171924 0.6405106 0.684288 0.6170123 0.6841313 0.6525078 0.7616386 0.6659531 0.508102 0.7845639 0.4312334
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.2048967 0.246819 0.2970746 0.3771899 0.3205272 0.2035354 0.4168961 0.3700703 0.3890616 0.4554534 0.4610826 0.2816754 0.1388129 0.2816877 0.4087341 0.3380162 0.3323564 0.407791 0.4629607 0.2156848 0.1537039 0.3501047 0.2788264 0.164782 0.2391471 0.4041634 0.3063181 0.2586737 0.3969766 0.3893789 0.3387619 0.3562468 0.5176653 0.3434421 0.3334609 0.1324402 0.1970803 0.2363729 0.201756 0.3273418 0.3932584 0.5180971 0.238717 0.2846977 0.30716 0.2682061 0.29521198 0.3207382 0.286445 0.3060229 0.2759363 0.3059528 0.2918104 0.3406151 0.2978233 0.2272301 0.3508677 0.1928534
△CT= CT gene of interest - Ct house keeping gene (ave of 3) Ave HARS2-SRBD1-SRP68 ADCY1 ALDOC APPL2 AQP4 ATP1B1 CCND1 CCND2 CDK1 CLCN5 CLDN10 DAPP1 eGFP EMC7 EPHB1 EPHB2 FABP7 FAM43A FZD1 FZD10 GJA1 GLI1 GLUL GPC4 GSN HES5 HEY1 HEY2 KALRN KCNJ10 MKI67 NFIA NRP2 OLIG2 PDLIM1 PLD2 S100B S1PR1 SEMA3C SHH SLC1A2 SLC1A3 SLC1A4 SLC6A11 SLC7A11 SMIM12 SOX9 SPARC SPARCL1 SYT11 THBS1 TLN2 TNF TNFRSF19 VIM ZBTB20
A_G1 11.6338 1.2782 −3.145967 0.0478 −3.229 −3.8089 −4.181967 −3.7346 −0.833367 1.9732333 3.7148 0.1735667 8.2688 −2.186233 3.6474667 −1.741933 −5.743133 −0.4595 1.4872 3.817 −2.222333 2.0610667 −1.4986 −4.469533 −1.641367 3.0420333 −0.579633 2.4843 3.7023333 −4.018933 0.069 −2.3427 1.6981667 −0.069733 0.315 −0.6233 1.3123333 −0.623833 −0.723133 −0.4263 −0.701033 −4.1394 −0.016067 4.1565 4.88143333 7.7203667 −2.935133 −6.186967 −2.0982 −3.437433 −4.102567 −0.967933 −0.9559 1.9281333 −6.8807 −1.124333
A_G2 11.441433 1.5341667 −3.324867 0.2038333 −3.188933 −3.826333 −3.869967 −3.4379 −0.981033 2.2899333 3.2788667 −0.0533 7.5246 −2.236333 3.3878667 −1.684567 −5.715667 −0.4084 1.3032 3.9521667 −2.525267 2.1103 −1.4671 −4.5339 −1.600267 4.2251333 −0.682733 2.5021 3.9660667 −3.923567 0.2776667 −2.3872 2.235 −0.0366 0.1926333 −0.574967 1.1158333 −0.668433 −0.6379 −0.371967 −0.570633 −4.319067 −0.1804 3.842 5.32556667 8.1395 −2.869567 −6.136033 −2.083733 −3.710633 −3.980533 −0.794833 −0.4498 1.9454333 −6.9462 −0.864267
A_G3 11.550667 1.6694667 −3.439467 0.0627667 −3.3482 −3.9414 −4.0534 −3.709667 −0.734867 2.2298 3.2316 −0.106033 7.1697667 −2.4144 3.4010333 −1.771767 −5.871733 −0.342167 1.3713333 3.9764333 −2.560067 1.9713 −1.621533 −4.560167 −1.8549 5.7286333 −0.792967 2.5243 3.9608667 −4.241333 0.4670667 −2.523167 1.5327333 −0.2236 0.3179 −0.7248 0.8451 −0.8686 −0.875 −0.1348 −1.076267 −4.396667 −0.2852 3.5290667 4.85846667 8.4567 −3.057333 −6.3652 −2.277133 −3.7523 −4.073667 −0.928467 0.1527 1.8246667 −6.948033 −1.055133
A_G4 11.491356 1.8033111 −3.478156 0.1121111 −3.441422 −3.971422 −4.114256 −3.567722 −1.021356 2.3998111 3.6736444 −0.019989 8.4246778 −2.427456 3.4665111 −1.825189 −5.465122 −0.609622 1.3200444 4.3724444 −2.498056 1.8544111 −1.602722 −4.734356 −1.926089 7.5159111 −0.792356 2.9431444 4.0086778 −4.146022 0.6578778 −2.333622 1.8610778 0.5577778 0.2215444 −0.661922 1.6225778 −0.726756 −0.936889 −0.117356 −0.445822 −4.153256 −0.140722 4.2752778 4.95651111 8.1941778 −3.093922 −6.346222 −1.995689 −3.597256 −4.248122 −0.863289 0.4692778 2.0314111 −6.916422 −0.681889
A_G5 12.0900 1.4137 −3.7492 0.1182 −3.3468 −3.6161 −3.7917 −3.4741 −0.7859 2.5337 2.8048 0.2727 6.8157 −2.2812 2.6462 −1.6215 −5.5908 −0.2838 1.0022 3.5116 −2.2713 2.1162 −1.5750 −4.5244 −1.4325 4.2637 −0.7621 2.7975 3.6863 −3.9411 0.3449 −2.0566 1.9795 −0.1166 0.2445 −0.5289 1.8138 −0.1973 −0.5146 1.3457 −1.1548 −4.2371 −0.3141 4.3503 5.5687 9.0128 −2.6617 −6.1984 −2.1553 −3.6034 −4.0359 −0.8854 0.9806 2.1092 −7.1279 −0.8667
Mean 11.641447 1.5397667 -3.4275267 0.1089333 -3.31088 -3.8328333 -4.0022667 -3.5848067 -0.8713 2.2852867 3.3407467 0.0533867 7.6407133 -2.3091333 3.3098067 -1.729 -5.6772933 -0.4207067 1.2968 3.92592 -2.4154133 2.0226467 -1.553 -4.56448 -1.6910333 4.9550733 -0.7219667 2.6502667 3.86484 -4.0542 0.3633067 -2.3286667 1.8612933 0.0222533 0.25832 -0.6227867 1.34192 -0.61698 -0.7375 0.0590467 -0.7897067 -4.2491 -0.1873067 4.0306267 5.11814 8.3047 -2.9235333 -6.2465667 -2.12202 -3.6202 -4.08816 -0.8879933 0.03938 1.96776 -6.96386 -0.9184667
SD 0.260774 0.206532 0.2213484 0.0611756 0.1016155 0.1401581 0.1652809 0.1343016 0.1244066 0.2093326 0.3720531 0.1618004 0.6937176 0.1075445 0.3851685 0.0786918 0.1550081 0.124745 0.1796975 0.3107193 0.1564112 0.110502 0.0670695 0.100535 0.1997657 1.7195114 0.0913891 0.2078567 0.1568902 0.1365106 0.2189902 0.1699073 0.2684161 0.3075832 0.0561693 0.075881 0.3873688 0.2520951 0.1721068 0.7323576 0.3120521 0.1095847 0.119595 0.3409636 0.31449735 0.4757621 0.1721429 0.1025839 0.1038791 0.1223128 0.1003979 0.0658105 0.7605047 0.107922 0.0957236 0.175103
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.1166217 0.0923639 0.09899 0.0273585 0.0454438 0.0626806 0.0739159 0.0600615 0.0556363 0.0936164 0.1663872 0.0723593 0.3102399 0.0480954 0.1722526 0.035192 0.0693217 0.0557877 0.0803631 0.1389579 0.0699492 0.049418 0.0299944 0.0449606 0.0893379 0.7689889 0.0408705 0.0929564 0.0701634 0.0610494 0.0979354 0.0759849 0.1200393 0.1375554 0.0251197 0.033935 0.1732366 0.1127403 0.0769685 0.3275203 0.139554 0.0490078 0.0534845 0.1524835 0.14064749 0.2127673 0.0769846 0.0458769 0.0464561 0.0546999 0.0448993 0.0294313 0.3401081 0.0482642 0.0428089 0.0783084
AN_G1 11.309322 2.4299444 −4.564089 −0.461922 −4.251389 −4.273322 −2.843756 −3.023756 0.5544778 3.1075444 1.6283111 −0.615356 6.9029778 −2.511489 1.2183444 −1.137356 −5.650456 0.1481111 0.0452444 1.8277444 −3.654622 1.3401444 −2.814989 −3.795889 −1.718256 0.7483111 −1.350956 0.7277778 2.5135778 −4.500789 1.7299111 −2.567722 1.8383778 −1.668956 0.6068778 −1.353322 −1.423922 −1.598289 −0.097222 2.1453444 −2.429889 −5.085156 −0.757756 −0.321456 3.67707778 8.4530778 −3.286522 −6.153722 −3.771589 −4.159622 −3.462689 −0.505056 1.2195111 −0.290322 −6.430222 −2.092922
AN_G2 12.104856 2.6816778 −4.525922 −0.240722 −3.980622 −4.231189 −2.954322 −2.832656 −0.252822 2.9214778 1.9124111 −0.349256 6.4093444 −2.301556 2.7401778 −1.033456 −5.371556 0.5722111 0.4608111 2.4683444 −3.700189 1.8951778 −1.902089 −3.925089 −1.844589 3.3941444 −1.241789 1.2926111 3.7955444 −4.259156 1.3575444 −2.448889 2.2137111 −0.731489 0.7924111 −1.023656 −0.756989 −1.531856 −0.014822 1.7528444 −1.783189 −4.889489 −0.742222 1.5347778 4.87324444 8.4315444 −3.034122 −6.230089 −3.214989 −3.947956 −3.225689 −0.276422 1.5896778 0.0882778 −6.737422 −1.324989
AN_G3 11.1881 2.6052 −4.2874 −0.2502 −4.038833 −4.307767 −3.0248 −3.131867 0.0405333 3.0842 2.0251333 −0.431333 6.8208 −2.360767 2.4641 −1.260633 −5.3426 0.6757667 0.3074 2.1862667 −3.614567 1.6469 −1.8925 −4.0645 −1.813267 3.6050333 −1.337067 1.6074333 3.5659333 −4.604 1.3034 −2.601567 1.919 −0.310933 0.5867667 −0.9819 −0.5573 −1.6099 −0.455633 1.6021333 −2.071933 −4.9814 −0.819 1.4713667 4.38543333 7.4762 −3.1607 −6.259767 −3.248 −3.9622 −3.5597 −0.521533 1.5158333 0.0135333 −6.580967 −1.975667
AN_G4 12.1807 2.5474333 −4.768867 −0.243167 −4.135867 −4.564167 −3.2359 −3.369733 −0.246967 3.1342 2.0731333 −0.5298 7.1299667 −2.569033 2.0397 −1.5015 −5.482033 0.1690333 0.303 2.2721 −3.7332 1.2665667 −2.547633 −4.416233 −2.194533 3.7162 −1.399467 1.6479333 3.3441333 −4.845867 1.6819333 −2.8296 1.9374333 0.1469333 0.6848333 −1.1772 −0.103733 −1.788467 −0.755967 1.8552333 −1.850267 −4.927767 −0.671433 2.0721 4.16653333 8.0921333 −3.484433 −6.709167 −3.332833 −3.9913 −3.721067 −0.811533 1.2791667 −0.129667 −6.775467 −1.528533
AN_G5 12.464278 2.1399556 −4.429778 0.0358222 −3.911944 −4.217344 −3.219178 −3.325411 −0.495044 3.1599889 1.8153889 −0.114978 6.0924889 −2.380411 1.7404889 −1.398478 −5.661711 −0.248578 0.2481889 2.2096556 −3.304678 1.4999889 −2.205844 −4.654544 −1.807578 4.4189889 −1.130211 1.9149222 3.4229889 −4.638978 0.8547889 −2.628178 2.4823556 0.0528222 0.2931556 −1.003978 0.4410222 −1.199878 −0.716611 2.3694889 −1.628044 −4.716544 −0.534411 2.8924556 5.10882222 8.0299556 −3.101311 −6.519144 −2.827344 −3.807744 −3.863311 −0.822711 2.6745889 0.4259222 −6.769311 −1.009011
Mean 11.849451 2.4808422 -4.5152111 -0.2320378 -4.0637311 -4.3187578 -3.0555911 -3.1366844 -0.0799644 3.0814822 1.8908756 -0.4081444 6.6711156 -2.4246511 2.0405622 -1.2662844 -5.5016711 0.2633089 0.2729289 2.1928222 -3.6014511 1.5297556 -2.2726111 -4.1712511 -1.8756444 3.1765356 -1.2918978 1.4381356 3.3284356 -4.5697578 1.3855156 -2.6151911 2.0781756 -0.5023244 0.5928089 -1.1080111 -0.4801844 -1.5456778 -0.4080511 1.9450089 -1.9526644 -4.9200711 -0.7049644 1.5298489 4.44222222 8.0965822 -3.2134178 -6.3743778 -3.2789511 -3.9737644 -3.5664911 -0.5874511 1.6557556 0.0215489 -6.6586778 -1.5862244
SD 0.5661479 0.2115588 0.1775117 0.176865 0.1332152 0.1417425 0.1698158 0.2208728 0.4022119 0.093849 0.1777253 0.1921515 0.4153441 0.1113305 0.5989434 0.189516 0.1503071 0.3707183 0.1498704 0.2322744 0.171887 0.2516759 0.4049814 0.355836 0.1843569 1.4108655 0.1069493 0.4543644 0.4867689 0.2141439 0.3520184 0.1380536 0.2666363 0.738224 0.1859678 0.1571683 0.7006329 0.215411 0.342696 0.3093817 0.3108672 0.1354914 0.1088484 1.1812605 0.56894883 0.3964284 0.1776849 0.2322094 0.3371176 0.1257111 0.2444192 0.2309942 0.5903588 0.2684048 0.150259 0.4508756
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.253189 0.094612 0.0793857 0.0790965 0.0595756 0.0633892 0.075944 0.0987773 0.1798746 0.0419705 0.0794812 0.0859328 0.1857475 0.0497885 0.2678557 0.0847542 0.0672194 0.1657903 0.0670241 0.1038763 0.0768702 0.1125529 0.1811132 0.1591347 0.0824469 0.6309582 0.0478292 0.2031979 0.2176897 0.0957681 0.1574274 0.0617394 0.1192434 0.3301438 0.0831673 0.0702878 0.3133325 0.0963347 0.1532583 0.1383597 0.139024 0.0605936 0.0486785 0.5282758 0.25444165 0.1772882 0.0794631 0.1038472 0.1507636 0.0562197 0.1093076 0.1033037 0.2640165 0.1200343 0.0671979 0.2016377
AE_G1 11.909511 2.8952889 −5.290811 −0.214578 −4.879611 −3.869278 −2.844411 −3.590044 −0.740011 1.8184556 1.4454222 −0.310478 3.4096222 −2.498444 −0.180678 0.5516889 −7.411111 −0.056811 1.7598222 1.5501222 −2.793878 7.2037556 −3.019778 −2.167844 −2.407678 0.3787222 −1.111678 0.2385889 1.3775222 −3.213278 −0.001344 −2.319178 0.6557556 0.0957889 0.7456556 −1.161678 0.5382222 −2.261578 2.4586889 6.4643889 −3.259144 −5.364644 −0.913644 −0.801978 −0.5218111 8.6419222 −3.051111 −5.691611 −4.378844 −4.660978 −0.894311 0.2708556 −0.509444 1.1434222 −6.662911 −0.684278
AE_G2 11.034078 2.7976889 −5.011911 0.0370222 −4.635044 −3.581844 −2.876578 −3.622778 −0.881611 1.9450556 1.9150889 −0.312911 3.1252889 −2.443811 −0.093244 0.5567222 −7.297378 0.0435556 1.9742889 1.7767222 −2.788544 6.6580556 −2.756211 −2.234344 −2.337678 1.0482889 −1.038444 0.3455222 1.3989222 −3.061778 −0.198844 −2.396144 0.7177222 −0.353678 1.2515222 −1.063778 0.5713889 −2.068278 2.3562222 5.8237889 −2.704211 −5.221811 −0.789878 −0.659611 0.17852222 8.2767222 −2.903744 −5.731478 −3.952244 −4.584911 −1.257778 0.2783222 1.0072889 1.1553889 −6.381011 −0.719811
AE_G3 11.401644 2.9860889 −5.445244 −0.229411 −4.821811 −3.517278 −2.505244 −3.427844 −0.295244 1.8145556 1.1938889 −0.368911 2.4033889 −2.500378 −0.231744 1.0190889 −7.162778 −0.024278 1.7546556 1.4086222 −2.760311 8.5403222 −2.905311 −1.581178 −2.255578 1.1034222 −1.182578 0.3841889 1.3965889 −2.919244 0.2756556 −2.004744 0.4317556 −0.255744 0.2451222 −1.114711 0.6808556 −2.048711 2.9106889 8.1323556 −3.656478 −5.460544 −0.935144 −0.982578 −0.4837444 8.4286556 −2.706478 −5.523844 −4.465511 −4.702111 −0.121111 0.7611889 1.4910222 1.0924889 −6.629544 −0.800744
AE_G4 11.764322 3.6475778 −5.122689 −0.095889 −4.653722 −3.495889 −2.487189 −3.273856 −0.320856 1.8950778 1.5002778 −0.552622 3.3987778 −2.379022 0.0012111 0.7464444 −7.170022 −0.246022 1.8698778 1.5606444 −2.830056 6.5504111 −2.849989 −1.918289 −2.249289 1.7973444 −1.038456 0.5969778 2.0066111 −2.824222 0.8988444 −2.022189 0.4106444 0.4372444 0.3088444 −1.013656 1.5456444 −1.911322 2.3280444 6.5229444 −2.955722 −5.339922 −0.514989 0.2071444 −0.0260556 8.3912444 −2.818722 −5.711456 −3.870322 −4.492689 −0.607456 0.9866111 0.9068778 1.4591111 −6.817156 −0.518322
AE_G5 11.812478 3.0891222 −5.511711 −0.280978 −4.574911 −3.524111 −2.613311 −3.102544 −0.587278 1.7103556 0.2648889 −0.270811 2.7146556 −2.328944 −0.526678 0.8972556 −6.992378 −0.950811 0.9525889 1.5075556 −2.790911 8.6280556 −2.975044 −1.596778 −2.411011 0.8809889 −0.952578 0.9556889 1.5383222 −2.974378 −0.255411 −2.104178 0.1680556 −0.736411 −0.118678 −1.143711 0.1848889 −1.919344 2.7794556 8.4320556 −3.594911 −5.383244 −0.614444 −0.942244 −0.7572444 7.8735222 −2.937944 −5.537411 −4.355878 −4.593178 −0.313311 0.6347222 1.2062556 1.0340889 −6.564344 −0.622811
Mean 11.584407 3.0831533 -5.2764733 -0.1567667 -4.71302 -3.59768 -2.6653467 -3.4034133 -0.565 1.8367 1.2639133 -0.3631467 3.0103467 -2.43012 -0.2062267 0.75424 -7.2067333 -0.2468733 1.6622467 1.5607333 -2.79274 7.51612 -2.9012667 -1.8996867 -2.3322467 1.0417533 -1.0647467 0.5041933 1.5435933 -2.99858 0.14378 -2.1692867 0.4767867 -0.16256 0.4864933 -1.0995067 0.7042 -2.0418467 2.56662 7.0751067 -3.2340933 -5.3540333 -0.75362 -0.6358533 -0.3220667 8.3224133 -2.8836 -5.63916 -4.20456 -4.6067733 -0.6387933 0.58634 0.8204 1.1769 -6.6109933 -0.6691933
SD 0.3627475 0.3334723 0.2107539 0.1277771 0.1306317 0.1551245 0.1849076 0.2184354 0.2567793 0.0893519 0.6155884 0.1115322 0.4414019 0.0752318 0.1998676 0.2065789 0.1574919 0.4079064 0.4068647 0.134842 0.0248311 1.006458 0.1038929 0.3071857 0.0785546 0.5099557 0.086677 0.2839809 0.2667081 0.1477918 0.4704571 0.1781031 0.2189733 0.4474997 0.5264232 0.0606165 0.5058273 0.1423648 0.2629244 1.1404759 0.4085007 0.0865915 0.1845184 0.4880831 0.38523663 0.2835939 0.1294223 0.1001884 0.2723718 0.0801646 0.4536923 0.3112617 0.7761299 0.1648839 0.1585957 0.1060764
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.1622256 0.1491333 0.094252 0.0571437 0.0584203 0.0693738 0.0826932 0.0976873 0.1148352 0.0399594 0.2752995 0.0498787 0.1974009 0.0336447 0.0893835 0.0923849 0.0704325 0.1824213 0.1819554 0.0603032 0.0111048 0.4501017 0.0464623 0.1373776 0.0351307 0.2280591 0.0387631 0.1270001 0.1192755 0.0660945 0.2103948 0.0796501 0.0979279 0.200128 0.2354236 0.0271085 0.2262129 0.0636675 0.1175834 0.5100363 0.1826871 0.0387249 0.0825192 0.2182774 0.17228306 0.126827 0.0578794 0.0448056 0.1218084 0.0358507 0.2028974 0.1392005 0.3470959 0.0737383 0.0709262 0.0474388
AEN_G1 13.112167 4.5352333 −5.6452 −1.3591 −4.2928 −3.498333 −0.9991 −1.649533 2.1442667 2.2755 −1.087533 −1.055633 1.9860667 −2.0901 0.0356667 2.1275 −5.618433 −0.171267 0.5793667 1.7247667 −4.154767 2.2278 −3.947533 −1.1114 −2.9552 −0.2314 −0.552567 0.4675667 2.2693667 −3.140533 3.9251333 −2.270067 0.5759333 −0.603633 0.9958333 −2.023133 −1.016633 −2.6358 3.2304 10.648533 −4.9102 −5.807 −1.4234 −1.868633 −1.4604 8.1655667 −3.570733 −5.925867 −5.352 −4.920233 −0.355367 1.5141667 0.8536333 −0.825633 −5.9377 −1.916067
AEN_G2 11.847544 4.1589222 −5.867744 −0.936578 −4.777111 −4.036344 −1.739344 −2.490178 1.0599222 2.3523222 −0.405244 −1.020478 1.3316556 −2.422811 −0.277744 1.3982222 −6.386978 0.0471222 1.0780556 1.7490222 −4.208611 2.6180556 −3.640578 −1.893478 −3.125678 0.3852889 −1.027178 0.0350556 1.8899222 −3.600678 2.0644556 −2.801144 0.6760556 0.0130222 1.7400222 −1.803411 −0.729678 −2.947478 2.5204556 8.9071889 −4.446978 −5.863778 −1.517811 −1.682411 −1.2225111 7.9338222 −3.736578 −6.231611 −5.128078 −5.095944 −0.546278 0.9641556 1.2949556 −0.633211 −6.258878 −1.391611
AEN_G3 11.939722 3.4713778 −6.378256 −0.939489 −5.387822 −4.398089 −1.964656 −3.134722 1.0405111 2.0769111 −0.767722 −1.036722 0.7370111 −2.849856 −0.752456 1.0997111 −7.268122 0.1091778 0.8625778 0.7019778 −4.285222 3.2036444 −3.910922 −2.116822 −3.246522 0.2136111 −1.617622 −0.361222 1.5811111 −4.049189 2.7600778 −2.902622 0.4294111 −0.193422 1.0067444 −1.997322 −0.585156 −3.197789 2.5771111 9.7466778 −5.195022 −6.293022 −1.874689 −2.162622 −2.1297556 7.9353778 −3.821322 −6.365022 −5.723122 −5.465056 −0.360422 0.8323444 1.1116444 −0.883389 −6.672156 −1.755022
AEN_G4 12.099311 4.4522889 −5.973778 −0.763678 −4.464711 −3.938444 −1.521811 −2.524244 1.2947222 2.2399222 −0.624078 −1.030711 1.2462556 −2.539111 −0.357311 1.0829556 −6.390944 −0.339978 1.0374556 1.6531222 −4.104178 2.5940889 −3.726311 −1.779244 −3.128511 0.7229222 −0.853311 0.4048222 2.1656556 −3.659378 2.8220222 −2.753944 0.6583222 −0.187578 1.1766889 −1.764978 −0.071878 −2.983844 2.0890222 10.656989 −4.807111 −5.853511 −1.251344 −1.125478 −1.6118444 8.6030222 −3.768311 −6.341844 −4.878778 −5.151811 −0.123878 1.3264889 0.7131556 −0.850278 −6.327544 −1.560811
AEN_G5 12.6591 4.1539 −6.235833 −0.7102 −4.248933 −3.901833 −1.547267 −2.429167 1.8463667 2.5768333 −1.178933 −0.572433 0.9937 −2.546333 −0.631767 1.2593667 −6.6469 −0.187267 0.3781333 1.2266667 −3.8873 1.9791667 −3.516733 −1.6006 −2.7823 0.9237667 −0.722233 0.6544333 2.0944667 −4.126367 2.3703 −2.6848 1.3880333 −0.683733 0.5843333 −1.682767 −0.651933 −2.7871 2.5193 10.168767 −4.984867 −6.045467 −1.263433 −1.916167 −1.9224333 8.5699 −3.5934 −6.3034 −5.1729 −5.142767 0.0362333 1.0575667 1.7127333 −0.8874 −6.061567 −1.575833
Mean 12.331569 4.1543444 -6.0201622 -0.9418089 -4.6342756 -3.9546089 -1.5544356 -2.4455689 1.4771578 2.3042978 -0.8127022 -0.9431956 1.2589378 -2.4896422 -0.3967222 1.3935511 -6.4622756 -0.1084422 0.7871178 1.4111111 -4.1280156 2.5245511 -3.7484156 -1.7003089 -3.0476422 0.4028378 -0.9545822 0.2401311 2.0001044 -3.7152289 2.7883978 -2.6825156 0.7455511 -0.3310689 1.1007244 -1.8543222 -0.6110556 -2.9104022 2.5872578 10.025631 -4.8688356 -5.9725556 -1.4661356 -1.7510622 -1.6693889 8.2415378 -3.6980689 -6.2335489 -5.2509756 -5.1551622 -0.2699422 1.1389444 1.1372244 -0.8159822 -6.2515689 -1.6398689
SD 0.5381395 0.4184232 0.2918579 0.2547244 0.4695958 0.321943 0.3577657 0.5284538 0.4948176 0.1825241 0.3214349 0.2076569 0.468221 0.2736399 0.3100247 0.4299767 0.5929382 0.1839346 0.3014286 0.4494505 0.1503641 0.4637488 0.1815562 0.3787426 0.1810626 0.4506088 0.4094968 0.4044064 0.2722632 0.3959419 0.705868 0.2437935 0.3721346 0.2985794 0.4186187 0.149124 0.3433726 0.2121139 0.4095895 0.7307249 0.2753842 0.2008904 0.2542813 0.3894011 0.3614749 0.3288948 0.1104289 0.1792794 0.3133924 0.1967848 0.2274443 0.2771018 0.3927475 0.1052601 0.2816618 0.2009528
N 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.2406633 0.1871245 0.1305228 0.1139162 0.2100096 0.1439773 0.1599977 0.2363317 0.2212892 0.0816273 0.1437501 0.092867 0.2093948 0.1223755 0.1386472 0.1922914 0.26517 0.082258 0.134803 0.2010004 0.0672449 0.2073948 0.0811944 0.1693789 0.0809736 0.2015184 0.1831325 0.1808561 0.1217598 0.1770706 0.3156738 0.1090278 0.1664236 0.1335288 0.187212 0.0666903 0.1535609 0.0948602 0.183174 0.3267901 0.1231556 0.0898409 0.1137181 0.1741455 0.16165649 0.1470862 0.0493853 0.0801762 0.1401534 0.0880049 0.1017162 0.1239237 0.175642 0.0470738 0.125963 0.0898688
△△CT= △CT co-culture - △CT monoculture ADCY1 ALDOC APPL2 AQP4 ATP1B1 CCND1 CCND2 CDK1 CLCN5 CLDN10 DAPP1 eGFP EMC7 EPHB1 EPHB2 FABP7 FAM43A FZD1 FZD10 GJA1 GLI1 GLUL GPC4 GSN HES5 HEY1 HEY2 KALRN KCNJ10 MKI67 NFIA NRP2 OLIG2 PDLIM1 PLD2 S100B S1PR1 SEMA3C SHH SLC1A2 SLC1A3 SLC1A4 SLC6A11 SLC7A11 SMIM12 SOX9 SPARC SPARCL1 SYT11 THBS1 TLN2 TNF TNFRSF19 VIM ZBTB20
A_G1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
AN_G1 1.1517444 −1.418122 −0.509722 −1.022389 −0.464422 1.3382111 0.7108444 1.3878444 1.1343111 −2.086489 −0.788922 −1.365822 −0.325256 −2.429122 0.6045778 0.0926778 0.6076111 −1.441956 −1.989256 −1.432289 −0.720922 −1.316389 0.6736444 −0.076889 −2.293722 −0.771322 −1.756522 −1.188756 −0.481856 1.6609111 −0.225022 0.1402111 −1.599222 0.2918778 −0.730022 −2.736256 −0.974456 0.6259111 2.5716444 −1.728856 −0.945756 −0.741689 −4.477956 −1.2043556 0.7327111 −0.351389 0.0332444 −1.673389 −0.722189 0.6398778 0.4628778 2.1754111 −2.218456 0.4504778 −0.968589
AE_G1 1.6170889 −2.144844 −0.262378 −1.650611 −0.060378 1.3375556 0.1445556 0.0933556 −0.154778 −2.269378 −0.484044 −4.859178 −0.312211 −3.828144 2.2936222 −1.667978 0.4026889 0.2726222 −2.266878 −0.571544 5.1426889 −1.521178 2.3016889 −0.766311 −2.663311 −0.532044 −2.245711 −2.324811 0.8056556 −0.070344 0.0235222 −1.042411 0.1655222 0.4306556 −0.538378 −0.774111 −1.637744 3.1818222 6.8906889 −2.558111 −1.225244 −0.897578 −4.958478 −5.4032444 0.9215556 −0.115978 0.4953556 −2.280644 −1.223544 3.2082556 1.2387889 0.4464556 −0.784711 0.2177889 0.4400556
AEN_G1 3.2570333 −2.499233 −1.4069 −1.0638 0.3105667 3.1828667 2.0850667 2.9776333 0.3022667 −4.802333 −1.2292 −6.282733 0.0961333 −3.6118 3.8694333 0.1247 0.2882333 −0.907833 −2.092233 −1.932433 0.1667333 −2.448933 3.3581333 −1.313833 −3.273433 0.0270667 −2.016733 −1.432967 0.8784 3.8561333 0.0726333 −1.122233 −0.5339 0.6808333 −1.399833 −2.328967 −2.011967 3.9535333 11.074833 −4.209167 −1.6676 −1.407333 −6.025133 −6.3418333 0.4452 −0.6356 0.2611 −3.2538 −1.4828 3.7472 2.4821 1.8095333 −2.753767 0.943 −0.791733
A_G2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
AN_G2 1.1475111 −1.201056 −0.444556 −0.791689 −0.404856 0.9156444 0.6052444 0.7282111 0.6315444 −1.366456 −0.295956 −1.115256 −0.065222 −0.647689 0.6511111 0.3441111 0.9806111 −0.842389 −1.483822 −1.174922 −0.215122 −0.434989 0.6088111 −0.244322 −0.830989 −0.559056 −1.209489 −0.170522 −0.335589 1.0798778 −0.061689 −0.021289 −0.694889 0.5997778 −0.448689 −1.872822 −0.863422 0.6230778 2.1248111 −1.212556 −0.570422 −0.561822 −2.307222 −0.4523222 0.2920444 −0.164556 −0.094056 −1.131256 −0.237322 0.7548444 0.5184111 2.0394778 −1.857156 0.2087778 −0.460722
AE_G2 1.2635222 −1.687044 −0.166811 −1.446111 0.2444889 0.9933889 −0.184878 0.0994222 −0.344878 −1.363778 −0.259611 −4.399311 −0.207478 −3.481111 2.2412889 −1.581711 0.4519556 0.6710889 −2.175444 −0.263278 4.5477556 −1.289111 2.2995556 −0.737411 −3.176844 −0.355711 −2.156578 −2.567144 0.8617889 −0.476511 −0.008944 −1.517278 −0.317078 1.0588889 −0.488811 −0.544444 −1.399844 2.9941222 6.1957556 −2.133578 −0.902744 −0.609478 −4.501611 −5.1470444 0.1372222 −0.034178 0.4045556 −1.868511 −0.874278 2.7227556 1.0731556 1.4570889 −0.790044 0.5651889 0.1444556
AEN_G2 2.6247556 −2.542878 −1.140411 −1.588178 −0.210011 2.1306222 0.9477222 2.0409556 0.0623889 −3.684111 −0.967178 −6.192944 −0.186478 −3.665611 3.0827889 −0.671311 0.4555222 −0.225144 −2.203144 −1.683344 0.5077556 −2.173478 2.6404222 −1.525411 −3.839844 −0.344444 −2.467044 −2.076144 0.3228889 1.7867889 −0.413944 −1.558944 0.0496222 1.5473889 −1.228444 −1.845511 −2.279044 3.1583556 9.2791556 −3.876344 −1.544711 −1.337411 −5.524411 −6.5480778 −0.205678 −0.867011 −0.095578 −3.044344 −1.385311 3.4342556 1.7589889 1.7447556 −2.578644 0.6873222 −0.527344
A_G3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
AN_G3 0.9357333 −0.847933 −0.312967 −0.690633 −0.366367 1.0286 0.5778 0.7754 0.8544 −1.206467 −0.3253 −0.348967 0.0536333 −0.936933 0.5111333 0.5291333 1.0179333 −1.063933 −1.790167 −1.0545 −0.3244 −0.270967 0.4956667 0.0416333 −2.1236 −0.5441 −0.916867 −0.394933 −0.362667 0.8363333 −0.0784 0.3862667 −0.087333 0.2688667 −0.2571 −1.4024 −0.7413 0.4193667 1.7369333 −0.995667 −0.584733 −0.5338 −2.0577 −0.4730333 −0.9805 −0.103367 0.1054333 −0.970867 −0.2099 0.5139667 0.4069333 1.3631333 −1.811133 0.3670667 −0.920533
AE_G3 1.3166222 −2.005778 −0.292178 −1.473611 0.4241222 1.5481556 0.2818222 0.4396222 −0.415244 −2.037711 −0.262878 −4.766378 −0.085978 −3.632778 2.7908556 −1.291044 0.3178889 0.3833222 −2.567811 −0.200244 6.5690222 −1.283778 2.9789889 −0.400678 −4.625211 −0.389611 −2.140111 −2.564278 1.3220889 −0.191411 0.5184222 −1.100978 −0.032144 −0.072778 −0.389911 −0.164244 −1.180111 3.7856889 8.2671556 −2.580211 −1.063878 −0.649944 −4.511644 −5.3422111 −0.028044 0.3508556 0.8413556 −2.188378 −0.949811 3.9525556 1.6896556 1.3383222 −0.732178 0.3184889 0.2543889
AEN_G3 1.8019111 −2.938789 −1.002256 −2.039622 −0.456689 2.0887444 0.5749444 1.7753778 −0.152889 −3.999322 −0.930689 −6.432756 −0.435456 −4.153489 2.8714778 −1.396389 0.4513444 −0.508756 −3.274456 −1.725156 1.2323444 −2.289389 2.4433444 −1.391622 −5.515022 −0.824656 −2.885522 −2.379756 0.1921444 2.2930111 −0.379456 −1.103322 0.0301778 0.6888444 −1.272522 −1.430256 −2.329189 3.4521111 9.8814778 −4.118756 −1.896356 −1.589489 −5.691689 −6.9882222 −0.521322 −0.763989 0.0001778 −3.445989 −1.712756 3.7132444 1.7608111 0.9589444 −2.708056 0.2758778 −0.699889
A_G4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
AN_G4 0.7441 −1.2907 −0.3553 −0.6944 −0.5927 0.8784 0.1980 0.7744 0.7344 −1.6005 −0.5098 −1.2947 −0.1416 −1.4268 0.3237 −0.0169 0.7787 −1.0170 −2.1003 −1.2351 −0.5878 −0.9449 0.3181 −0.2684 −3.7997 −0.6071 −1.2952 −0.6645 −0.6998 1.0241 −0.4960 0.0764 −0.4108 0.4633 −0.5153 −1.7263 −1.0617 0.1809 1.9726 −1.4044 −0.7745 −0.5307 −2.2032 −0.7900 −0.1020 −0.3905 −0.3629 −1.3371 −0.3940 0.5271 0.0518 0.8099 −2.1611 0.1410 −0.8466
AE_G4 1.8442667 −1.644533 −0.208 −1.2123 0.4755333 1.6270667 0.2938667 0.7005 −0.504733 −2.173367 −0.532633 −5.0259 0.0484333 −3.4653 2.5716333 −1.7049 0.3636 0.5498333 −2.8118 −0.332 4.696 −1.247267 2.8160667 −0.3232 −5.718567 −0.2461 −2.346167 −2.002067 1.3218 0.2409667 0.3114333 −1.450433 −0.120533 0.0873 −0.351733 −0.076933 −1.184567 3.2649333 6.6403 −2.5099 −1.186667 −0.374267 −4.068133 −4.9825667 0.1970667 0.2752 0.6347667 −1.874633 −0.895433 3.6406667 1.8499 0.4376 −0.5723 0.0992667 0.1635667
AEN_G4 2.6489778 −2.495622 −0.875789 −1.023289 0.0329778 2.5924444 1.0434778 2.3160778 −0.159889 −4.297722 −1.010722 −7.178422 −0.111656 −3.823822 2.9081444 −0.925822 0.2696444 −0.282589 −2.719322 −1.606122 0.7396778 −2.123589 2.9551111 −1.202422 −6.792989 −0.060956 −2.538322 −1.843022 0.4866444 2.1641444 −0.420322 −1.202756 −0.745356 0.9551444 −1.103056 −1.694456 −2.257089 3.0259111 10.774344 −4.361289 −1.700256 −1.110622 −5.400756 −6.5683556 0.4088444 −0.674389 0.0043778 −2.883089 −1.554556 4.1242444 2.1897778 0.2438778 −2.881689 0.5888778 −0.878922
A_G5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
AN_G5 0.7263 −0.6806 −0.0823 −0.5651 −0.6012 0.5726 0.1487 0.2908 0.6263 −0.9894 −0.3877 −0.7232 −0.0992 −0.9057 0.2231 −0.0709 0.0353 −0.7540 −1.3019 −1.0333 −0.6162 −0.6308 −0.1301 −0.3750 0.1553 −0.3681 −0.8826 −0.2633 −0.6978 0.5099 −0.5715 0.5029 0.1694 0.0486 −0.4750 −1.3727 −1.0026 −0.2020 1.0238 −0.4733 −0.4794 −0.2203 −1.4578 −0.4599 −0.9828 −0.4396 −0.3207 −0.6720 −0.2044 0.1726 0.0627 1.6940 −1.6832 0.3586 −0.1423
AE_G5 1.6754 −1.7625 −0.3991 −1.2281 0.0920 1.1784 0.3716 0.1986 −0.8233 −2.5399 −0.5435 −4.1011 −0.0477 −3.1728 2.5188 −1.4016 −0.6670 −0.0496 −2.0040 −0.5196 6.5119 −1.4000 2.9277 −0.9785 −3.3827 −0.1904 −1.8418 −2.1479 0.9668 −0.6003 −0.0475 −1.8114 −0.6198 −0.3632 −0.6148 −1.6289 −1.7221 3.2940 7.0864 −2.4401 −1.1461 −0.3003 −5.2925 −6.3260 −1.1392 −0.2762 0.6610 −2.2005 −0.9898 3.7226 1.5202 0.2256 −1.0751 0.5636 0.2439
AEN_G5 2.7402 −2.4867 −0.8284 −0.9021 −0.2857 2.2445 1.0450 2.6322 0.0432 −3.9838 −0.8451 −5.8220 −0.2651 −3.2779 2.8809 −1.0561 0.0966 −0.6241 −2.2849 −1.6160 −0.1370 −1.9417 2.9238 −1.3498 −3.3399 0.0399 −2.1431 −1.5918 −0.1852 2.0254 −0.6282 −0.5915 −0.5672 0.3398 −1.1538 −2.4657 −2.5898 3.0339 8.8231 −3.8301 −1.8084 −0.9493 −6.2665 −7.4912 −0.4429 −0.9317 −0.1050 −3.0176 −1.5394 4.0721 1.9430 0.7321 −2.9966 1.0664 −0.7091
Fold Change ADCY1 ALDOC APPL2 AQP4 ATP1B1 CCND1 CCND2 CDK1 CLCN5 CLDN10 DAPP1 eGFP EMC7 EPHB1 EPHB2 FABP7 FAM43A FZD1 FZD10 GJA1 GLI1 GLUL GPC4 GSN HES5 HEY1 HEY2 KALRN KCNJ10 MKI67 NFIA NRP2 OLIG2 PDLIM1 PLD2 S100B S1PR1 SEMA3C SHH SLC1A2 SLC1A3 SLC1A4 SLC6A11 SLC7A11 SMIM12 SOX9 SPARC SPARCL1 SYT11 THBS1 TLN2 TNF TNFRSF19 VIM ZBTB20
A_G1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
AN_G1 0.4500807 2.6723745 1.423776 2.0312797 1.3797647 0.3955108 0.6109624 0.3821353 0.4555524 4.2471318 1.7277832 2.5772317 1.2528864 5.3856565 0.6576638 0.9377805 0.6562825 2.7168889 3.9703207 2.6987454 1.6482353 2.4904197 0.626921 1.0547411 4.9031953 1.7068334 3.3788264 2.2795603 1.3965387 0.3162394 1.1687953 0.9073864 3.0297993 0.8168382 1.6586646 6.6633864 1.9648995 0.6480104 0.1682124 3.3146477 1.9261974 1.6721322 22.284297 2.30434313 0.601772 1.2757882 0.9772202 3.1896296 1.6496831 0.6417673 0.7255376 0.2213788 4.6539495 0.7318005 1.9569256
AE_G1 0.3259926 4.4224457 1.199454 3.139666 1.0427388 0.3956905 0.904658 0.9373401 1.1132501 4.8211515 1.3986592 29.024067 1.2416092 14.203203 0.2039628 3.1776887 0.7564471 0.8278136 4.8128044 1.4861136 0.0283072 2.8702527 0.2028255 1.7009151 6.3348529 1.4459768 4.7427082 5.0100018 0.5721021 1.0499673 0.9838278 2.059667 0.8916057 0.7419246 1.4523385 1.7101361 3.1117894 0.1101986 0.0084274 5.889361 2.3379506 1.8629356 31.092135 42.3193172 0.5279395 1.0837093 0.7093868 4.8589495 2.3351973 0.1081979 0.4237282 0.7338436 1.7227473 0.8598823 0.7371062
AEN_G1 0.1046009 5.6538489 2.6516677 2.0904304 0.806325 0.1101188 0.2356852 0.126953 0.8109772 27.90271 2.3443695 77.855839 0.935537 12.225317 0.0684202 0.9171947 0.8189042 1.8762256 4.2640765 3.8169845 0.8908576 5.4601226 0.0975217 2.4860121 9.6694467 0.9814137 4.0466648 2.7000136 0.5439704 0.0690539 0.9509007 2.1768369 1.4478378 0.6238048 2.638711 5.0244534 4.0333166 0.0645458 0.0004636 18.496324 3.1768567 2.6524643 65.124719 81.1114305 0.7344825 1.5535837 0.8344514 9.5387485 2.7949065 0.0744698 0.1789837 0.2852832 6.7447579 0.5201501 1.7311531
A_G2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
AN_G2 0.4514033 2.2990782 1.3608948 1.7310998 1.3239563 0.530107 0.65736 0.603652 0.645485 2.5783633 1.2276979 2.1663338 1.0462461 1.5666565 0.6367897 0.7877932 0.506765 1.7930167 2.7968875 2.2578071 1.1608023 1.3519004 0.6557369 1.1845361 1.7789043 1.4733044 2.3125569 1.1254658 1.2618924 0.4730689 1.0436868 1.0148657 1.6187598 0.6598556 1.3647994 3.6624834 1.8193489 0.6492843 0.229281 2.3174779 1.4849581 1.4761325 4.9492922 1.36824086 0.8167438 1.1208207 1.0673664 2.1904929 1.1788027 0.5926103 0.6981403 0.2432518 3.6229265 0.86527 1.3762306
AE_G2 0.4165258 3.2199637 1.1225744 2.7247259 0.8441148 0.5022965 1.1367207 0.9334067 1.2700434 2.573582 1.197156 21.102048 1.1546677 11.166546 0.2114973 2.9932465 0.7310512 0.6280325 4.517249 1.2002024 0.0427552 2.4437744 0.2031257 1.6671814 9.0432694 1.2796162 4.4585598 5.9263525 0.5502698 1.3913748 1.0062191 2.8625041 1.2458046 0.4800016 1.403288 1.4584586 2.6387313 0.1255103 0.0136424 4.3880433 1.8696192 1.5257068 22.6527 35.4335583 0.9092682 1.0239731 0.755469 3.6515554 1.8330902 0.1514847 0.4752783 0.3642273 1.7291277 0.6758669 0.9047207
AEN_G2 0.1621324 5.8275027 2.2044383 3.0066934 1.1566971 0.2283594 0.5184504 0.2430027 0.957677 12.853694 1.9550124 73.158036 1.137982 12.68992 0.1180288 1.5925196 0.7292462 1.1688943 4.604819 3.2117163 0.7033158 4.5110953 0.1603813 2.8786874 14.318857 1.269662 5.5290992 4.2167879 0.7994674 0.2898164 1.3323235 2.9463819 0.9661893 0.3421287 2.3431421 3.5938025 4.8535638 0.1120057 0.0016095 14.685744 2.9174564 2.5269745 46.027083 93.5767214 1.153228 1.8238804 1.0684932 8.2497159 2.6122828 0.0925094 0.2954552 0.2983845 5.9737814 0.6210054 1.4412738
A_G3 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
AN_G3 0.5227767 1.7999207 1.2422596 1.6139919 1.2891022 0.4901856 0.6699847 0.5842266 0.5530953 2.3077176 1.2529249 1.273648 0.9635067 1.9144544 0.701671 0.6929709 0.4938232 2.0906236 3.4585484 2.0769982 1.2521436 1.206616 0.7092339 0.9715544 4.3578 1.4581104 1.8880103 1.314882 1.2858004 0.5600652 1.0558464 0.765107 1.0624046 0.8299713 1.195074 2.6434096 1.6716815 0.7477528 0.3000067 1.9940017 1.4997617 1.4477375 4.1632206 1.38802479 1.9731491 1.0742775 0.9295257 1.9600177 1.156608 0.7002943 0.7542249 0.3887371 3.5091785 0.7753574 1.8928149
AE_G3 0.4014738 4.0160515 1.2244873 2.7771616 0.7452921 0.341947 0.8225514 0.7373277 1.3335246 4.1059359 1.1998697 27.215899 1.0614069 12.40438 0.1445003 2.4470515 0.8022429 0.7666701 5.9290917 1.148893 0.0105324 2.434757 0.1268338 1.320128 24.678984 1.3100402 4.4079599 5.9145884 0.3999554 1.1418801 0.6981349 2.1450002 1.0225309 1.0517398 1.3103127 1.1205791 2.2659423 0.0725094 0.0032459 5.980272 2.0905431 1.5691078 22.810789 40.5663364 1.0196291 0.784119 0.5581189 4.5579269 1.9316197 0.0645895 0.3100009 0.3954803 1.6611447 0.8019094 0.8383422
AEN_G3 0.2867944 7.6676734 2.0031293 4.1113786 1.3723884 0.2350852 0.6713121 0.2921178 1.1117935 15.992485 1.906186 86.387793 1.3523378 17.796096 0.1366467 2.6324185 0.731361 1.4228224 9.6763004 3.3061577 0.4256252 4.88849 0.1838569 2.6237354 45.728517 1.7711121 7.3897329 5.2044855 0.8753037 0.2040492 1.3008508 2.1484887 0.9792996 0.6203505 2.4158355 2.6949445 5.0252274 0.0913716 0.0010602 17.372766 3.722716 3.0094271 51.685543 126.959296 1.4352701 1.6981794 0.9998768 10.89798 3.277863 0.0762434 0.2950822 0.5144332 6.5344036 0.8259476 1.6243797
A_G4 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
AN_G4 0.597031 2.4464861 1.2792319 1.6182612 1.5081129 0.5439871 0.871765 0.5846362 0.6010726 3.0325073 1.4238638 2.4532787 1.1031109 2.688518 0.7990242 1.0117909 0.5829098 2.0237687 4.2881175 2.3540492 1.5029994 1.9250703 0.8021132 1.2045084 13.92602 1.523206 2.454129 1.5850677 1.6243296 0.4917321 1.4102762 0.9484505 1.3294638 0.7253308 1.4292693 3.3088069 2.0874058 0.8821389 0.2547954 2.6471583 1.7106103 1.4446411 4.6049254 1.72904783 1.0732934 1.3108577 1.286048 2.5265075 1.3140721 0.6939696 0.9647616 0.5704258 4.4724885 0.9069183 1.7983134
AE_G4 0.2784969 3.1264671 1.1550858 2.3170674 0.7192009 0.3237458 0.8157129 0.6153589 1.4188611 4.5107479 1.4465672 32.579668 0.9669858 11.044835 0.1682136 3.2600634 0.7772227 0.683099 7.0216009 1.2587572 0.0385801 2.3739123 0.1419971 1.2511025 52.657483 1.1859967 5.0847141 4.0057341 0.4000355 0.8461781 0.8058407 2.7329013 1.0871367 0.9412827 1.2760929 1.0547736 2.2729511 0.1040296 0.0100247 5.695806 2.2762621 1.2961805 16.77375 31.6156432 0.8723224 0.8263358 0.644045 3.6670841 1.8601685 0.0801771 0.2774116 0.7383619 1.4868921 0.9335074 0.8928151
AEN_G4 0.159433 5.6397149 1.8350112 2.0325472 0.9774008 0.1658046 0.4851565 0.2008127 1.1172011 19.667235 2.0149195 144.85064 1.0804674 14.160715 0.1332175 1.8997667 0.829524 1.2163757 6.5856335 3.0443247 0.5988731 4.3577665 0.1289505 2.3012572 110.89026 1.0431565 5.8091304 3.5876079 0.7136831 0.2231144 1.3382264 2.3017889 1.6763874 0.5157899 2.1480917 3.2365472 4.7802593 0.122775 0.000571 20.553168 3.2495852 2.1593876 42.246372 94.9012744 0.7532264 1.5959206 0.9969702 7.3772795 2.9374322 0.0573428 0.2191852 0.8444724 7.370124 0.6648599 1.8390009
A_G5 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
AN_G5 0.6044661 1.6028062 1.058729 1.4794901 1.5170129 0.6724194 0.9020421 0.8174298 0.6478208 1.985405 1.3082758 1.6508778 1.0711546 1.87341 0.8567424 1.0503717 0.9758514 1.6865012 2.4655337 2.0467478 1.532797 1.5484234 1.0943696 1.2968695 0.8979249 1.2906221 1.8436524 1.2001932 1.6220669 0.7022873 1.4861022 0.7057031 0.8892124 0.9668518 1.3899503 2.5896073 2.0036076 1.1503185 0.4918078 1.3882493 1.3941959 1.1649489 2.7469551 1.37544648 1.9762973 1.3562282 1.2489652 1.5932802 1.1521804 0.8872423 0.9574484 0.309076 3.2114689 0.779903 1.1036632
AE_G5 0.3130721 3.3929339 1.3187155 2.3425286 0.9382212 0.441831 0.7729248 0.8713958 1.7694488 5.8156213 1.4575042 17.161059 1.0336158 9.0181614 0.174488 2.6418832 1.5877312 1.0350018 4.0111057 1.4335246 0.0109578 2.6390158 0.131427 1.9703701 10.429996 1.1411064 3.5845698 4.4319246 0.5116515 1.5160668 1.0334964 3.5099083 1.5366976 1.2862758 1.5313103 3.0926995 3.2990866 0.1019523 0.0073584 5.4269188 2.2131992 1.2314004 39.193251 80.2242597 2.2026394 1.2110289 0.6324398 4.5964923 1.9859097 0.0757505 0.3486456 0.8552195 2.1068194 0.6766117 0.8444594
AEN_G5 0.1496629 5.6047715 1.7756602 1.8687698 1.2190204 0.2110303 0.4846524 0.161293 0.9705149 15.820854 1.7964169 56.572233 1.2017101 9.6995796 0.1357561 2.079287 0.9352489 1.5412372 4.8732657 3.0651455 1.0996077 3.841551 0.1317756 2.5486894 10.125273 0.9727149 4.4169655 3.0142287 1.1369921 0.2456408 1.5455877 1.5067662 1.4815995 0.7901448 2.225026 5.5239065 6.0202451 0.1220989 0.0022079 14.222359 3.5024284 1.9309207 76.982337 179.912991 1.3592921 1.9075077 1.0754861 8.0979434 2.9067135 0.0594514 0.2600731 0.6020223 7.9809227 0.4775164 1.6348091
Mean Fold Change ADCY1 ALDOC APPL2 AQP4 ATP1B1 CCND1 CCND2 CDK1 CLCN5 CLDN10 DAPP1 eGFP EMC7 EPHB1 EPHB2 FABP7 FAM43A FZD1 FZD10 GJA1 GLI1 GLUL GPC4 GSN HES5 HEY1 HEY2 KALRN KCNJ10 MKI67 NFIA NRP2 OLIG2 PDLIM1 PLD2 S100B S1PR1 SEMA3C SHH SLC1A2 SLC1A3 SLC1A4 SLC6A11 SLC7A11 SMIM12 SOX9 SPARC SPARCL1 SYT11 THBS1 TLN2 TNF TNFRSF19 VIM ZBTB20
Mean (A) 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
SD 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
n 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mean (AN) 0.525 2.164 1.273 1.695 1.404 0.526 0.742 0.594 0.581 2.830 1.388 2.024 1.087 2.686 0.730 0.896 0.643 2.062 3.396 2.287 1.419 1.704 0.778 1.142 5.173 1.490 2.375 1.501 1.438 0.509 1.233 0.868 1.586 0.800 1.408 3.774 1.909 0.816 0.289 2.332 1.603 1.441 7.750 1.633 1.288 1.228 1.102 2.292 1.290 0.703 0.820 0.347 3.894 0.812 1.626
SD 0.075 0.448 0.139 0.208 0.105 0.100 0.134 0.154 0.080 0.880 0.204 0.551 0.106 1.565 0.094 0.152 0.197 0.401 0.767 0.263 0.204 0.515 0.189 0.129 5.176 0.149 0.620 0.469 0.176 0.140 0.204 0.129 0.853 0.116 0.166 1.678 0.165 0.210 0.123 0.719 0.215 0.181 8.168 0.405 0.649 0.123 0.160 0.606 0.212 0.112 0.130 0.141 0.632 0.072 0.369
n 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.034 0.200 0.062 0.093 0.047 0.045 0.060 0.069 0.036 0.394 0.091 0.246 0.047 0.700 0.042 0.068 0.088 0.180 0.343 0.118 0.091 0.231 0.085 0.058 2.315 0.067 0.277 0.210 0.079 0.063 0.091 0.058 0.382 0.052 0.074 0.750 0.074 0.094 0.055 0.322 0.096 0.081 3.653 0.181 0.290 0.055 0.071 0.271 0.095 0.050 0.058 0.063 0.283 0.032 0.165
Mean (AE) 0.347 3.636 1.204 2.660 0.858 0.401 0.891 0.819 1.381 4.365 1.340 25.417 1.092 11.567 0.181 2.904 0.931 0.788 5.258 1.305 0.026 2.552 0.161 1.582 20.629 1.273 4.456 5.058 0.487 1.189 0.906 2.662 1.157 0.900 1.395 1.687 2.718 0.103 0.009 5.476 2.158 1.497 26.505 46.032 1.106 0.986 0.660 4.266 1.989 0.096 0.367 0.617 1.741 0.790 0.843
SD 0.059 0.560 0.075 0.341 0.135 0.073 0.146 0.140 0.244 1.184 0.131 6.211 0.108 1.909 0.027 0.349 0.368 0.158 1.211 0.147 0.015 0.204 0.038 0.296 19.267 0.119 0.557 0.864 0.082 0.268 0.146 0.590 0.248 0.306 0.104 0.829 0.475 0.019 0.004 0.644 0.185 0.250 8.735 19.576 0.640 0.179 0.076 0.566 0.203 0.035 0.081 0.223 0.227 0.113 0.066
n 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.027 0.250 0.034 0.153 0.060 0.033 0.065 0.062 0.109 0.530 0.059 2.778 0.048 0.854 0.012 0.156 0.165 0.071 0.541 0.066 0.007 0.091 0.017 0.132 8.616 0.053 0.249 0.387 0.037 0.120 0.065 0.264 0.111 0.137 0.047 0.371 0.212 0.009 0.002 0.288 0.083 0.112 3.907 8.755 0.286 0.080 0.034 0.253 0.091 0.016 0.036 0.100 0.101 0.051 0.030
Mean (AEN) 0.173 6.079 2.094 2.622 1.106 0.190 0.479 0.205 0.994 18.447 2.003 87.765 1.142 13.314 0.118 1.824 0.809 1.445 6.001 3.289 0.744 4.612 0.140 2.568 38.146 1.208 5.438 3.745 0.814 0.206 1.294 2.216 1.310 0.578 2.354 4.015 4.943 0.103 0.001 17.066 3.314 2.456 56.413 115.292 1.087 1.716 0.995 8.832 2.906 0.072 0.250 0.509 6.921 0.622 1.654
SD 0.068 0.892 0.354 0.944 0.219 0.052 0.156 0.065 0.127 5.812 0.207 33.709 0.153 2.977 0.029 0.633 0.085 0.285 2.241 0.314 0.261 0.605 0.033 0.211 43.339 0.337 1.317 1.000 0.219 0.083 0.215 0.512 0.320 0.165 0.190 1.206 0.712 0.025 0.001 2.648 0.309 0.422 14.404 39.899 0.330 0.150 0.097 1.393 0.244 0.014 0.050 0.232 0.775 0.137 0.147
n 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5
SEM 0.030 0.399 0.158 0.422 0.098 0.023 0.070 0.029 0.057 2.599 0.092 15.075 0.069 1.331 0.013 0.283 0.038 0.127 1.002 0.141 0.117 0.271 0.015 0.094 19.382 0.151 0.589 0.447 0.098 0.037 0.096 0.229 0.143 0.074 0.085 0.540 0.319 0.011 0.000 1.184 0.138 0.189 6.442 17.843 0.148 0.067 0.043 0.623 0.109 0.006 0.023 0.104 0.347 0.061 0.066