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. 2023 Feb 16;23(6):2895–2907. doi: 10.1007/s10238-023-01007-2

Table 2.

Clinical staging systems and risk status

Risk status Modified Rai stage Binet stage
Low risk 0: Lymphocytosis A: < 3 involved nodal areas
Intermediate risk I: Lymphadenopathy B: ≥ 3 involved nodal areas
II: Splenomegaly and/or hepatomegaly
High risk III: Haemoglobin < 11 g/dL C: Haemoglobin < 10 g/dL and/or platelets < 100 × 109/L