Development of webcam-collected and artificial-intelligence-derived social and cognitive performance measures for neurodevelopmental genetic syndromes

. Author manuscript; available in PMC: 2024 Sep 1.

Published in final edited form as: Am J Med Genet C Semin Med Genet. 2023 Aug 3;193(3):e32058. doi: 10.1002/ajmg.c.32058

	1: OA	2: AS	3: PE	4: NE	5: SA	5: SP	6: FP	7: NP	8: RV	9: SF	10: SO	11: RA
1: Overall attention (OA)	-	.34^*	−.19^*	−.08	−.45^*	.13	.33^*	−.25^*	.54^*	−.26^*	−.28^*	.55^*
2: Attentional Scanning (AS)		-	−.24^*	−.21^*	−.49^*	.23^*	.27^*	−.25^*	.54^*	−.21^*	−.78^*	.48^*
3: Positive Emotion (PE)			-	−.06	.23^*	−.15	−.15	.08	−.23^*	.02	.22^*	−.27^*
4: Negative Emotion (NE)				-	.22^*	−.15	−.11	.15	−.23^*	.08	.19^*	−.28^*
5: Social Attention (SA)					-	−.54	−.52^*	.19^*	−.59^*	.30^*	.45^*	−.62^*
5: Social Preference (SP)						-	.64^*	−.05	.35^*	−.30^*	−.24^*	.38^*
6: Face Preference (FP)							-	−.50^*	.38^*	−.79^*	−.34^*	.38^*
7: Non-social Preference (NP)								-	−.18	.62^*	.33^*	−.20
8: Receptive Vocabulary (RV)									-	−.22	−.55^*	.78^*
9: Speed to Faces (SF)										-	.30^*	−.21
10: Speed to Object (SO)											-	−.47^*
11: Reading accuracy (RA)												-

Note. Social attention is keyed so that higher scores are more consistent with autism spectrum disorder. Speed to faces and speed to objects are keyed so that higher scores indicate longer time to fixate the target. Samples sizes vary from n=248 to n=322.

designates significant correlations p<.001.