Table 3. Protein parameters used in the simulations of SAXS and SANS curves shown in Fig. S10 .

	Aquaporin (PDB 3d9s)	Bacteriorhodopsin (PDB 1fbb)	ATPase (PDB 3wgv)	Cytochrome c (PDB 1giw)
M w (g mol−1)	102 505	73 690	109 942	11 721
V p (Å3)	133 006	96 506	138 965	14 839
R (Å)	5.78	8.01	18.2	0.262
δ (Å)	28.6	21.0	24.6	15.0
ϕi	0.211	0.0195	1.00	0.718
ϕe	0.904	0.870	0.0557	0.886
L † (Å)	41.4	45.5	107	22.8
ρp,X (e Å−3)	0.411	0.411	0.420	0.420
ρp,N (10−6 Å−2)	2.828	2.732	3.009	3.119

^†Input parameters are derived parameters.