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. 2023 Sep 21;7:100598. doi: 10.1016/j.crfs.2023.100598

Table 2.

Free copper chelating activity of CRNL and its variants using a pyrocatechol violet assay.

Peptide	Relative copper (%)						IC₅₀ (μM)
Peptide	0 μM	12.5 0 μM	25 μM	50 μM	100 μM	200 μM	IC₅₀ (μM)
CRNL	100.00 ± 8.85^a	107.70 ± 1.25^ab	102.13 ± 6.92^ab	103.89 ± 2.54^ab	95.01 ± 2.11^b	69.63 ± 3.00^c	>200
CENL	100.00 ± 8.85^a	102.13 ± 6.74^a	100.95 ± 8.05^a	102.13 ± 7.57^a	95.16 ± 4.06^a	73.15 ± 1.43^b	>200
CRLL	100.00 ± 10.46^a	95.08 ± 5.99^ab	93.10 ± 4.47^abc	91.24 ± 2.38^abc	87.82 ± 2.56^bc	83.31 ± 0.45^d	>200
CRNN	100.00 ± 10.46^a	96.28 ± 3.61^a	92.92 ± 2.56^a	91.18 ± 1.00^a	77.61 ± 4.79^b	41.12 ± 2.18^c	171.97 ± 7.70
CELL	100.00 ± 8.85^a	106.60 ± 3.21^a	106.68 ± 1.47^a	104.11 ± 3.42^a	99.34 ± 4.33^a	84.15 ± 0.46^b	>200
CRLN	100.00 ± 8.85^a	109.17 ± 4.08^ab	103.23 ± 3.24^ab	101.69 ± 3.24^ab	97.29 ± 5.86^b	87.45 ± 3.00^c	>200
CENN	100.00 ± 10.46^a	94.42 ± 1.88^ab	94.96 ± 2.98^ab	90.28 ± 2.52^b	79.11 ± 0.95^c	53.72 ± 2.55^d	>200
CELN	100.00 ± 10.46^a	97.42 ± 4.15^ab	93.16 ± 3.72^ab	93.94 ± 0.28^ab	88.90 ± 2.45^c	72.81 ± 3.26^d	>200

Values are the mean ± the standard deviation. The different superscript letters are used to indicate the significant difference at p < 0.05.