Table 3.

Summary of findings and quality of evidence according to Physical Activity Guidelines Advisory Committee Grading Criteria (PAGAC)

Systematic review research questions	Applicability	Generalizability	Risk of bias or study limitations	Quantity and consistency	Magnitude and precision of effect	Effect [95% CI]	Evidence
Depression	Strong	Strong	Limited	Limited	Strong	−0.76 [−1.54, 0.03]	Moderate
Peak force	Strong	Strong	Limited	Limited	Strong	0.62 [0.18, 1.06]	Moderate
6MWT	Strong	Strong	Limited	Limited	Strong	0.61 [0.43, 0.80]	Moderate
VO2 max	Strong	Strong	Limited	Limited	Strong	0.59 [0.33, 0.85]	Moderate
HRQOL	Strong	Strong	Limited	Limited	Strong	0.43 [0.33, 0.53]	Moderate
DBP	Strong	Strong	Limited	Limited	Strong	−0.38 [−0.90, 0.15]	Moderate
SBP	Strong	Strong	Limited	Limited	Strong	−0.17 [−0.51, 0.17]	Moderate

95% CI: 95% Confidence interval; HRQOL: Health Related Quality of Life; 6MWT: 6 Minute Walking Test; SBP: Systolic Blood Pressure; DBP: Diastolic blood pressure; VO₂ max: Maximal oxygen uptake