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. 2023 Oct 2;13(41):28798–28833. doi: 10.1039/d3ra05570a

A summary of ultrasound-assisted pyrano[2,3-c]pyrazole and spiropyrano[2,3-c] pyrazole synthesis.

Product Reactants Catalyst Solvent Method employed Reaction time Yield Ref.
Dihydropyrano[2,3-c]pyrazoles Four-component system: 4-hydrazinobenzoic acid, β-keto esters, aromatic aldehydes, and malononitrile Ceric ammonium nitrate (CAN) Water Ultrasound 45–60 min 70–90% Ablajan et al.44
Spiro[indoline-3,4′-pyrano[2,3-c]]pyrazoles Three-component system: isatin, ethyl-cyanoacetate, and 3-methyl-1-phenyl-2-pyrazolin-5-one ZnS nanoparticles Water Ultrasound 12–15 min 93–97% Dandia et al.45
Pyrano[2,3-c]pyrazoles Four-component system: aromatic aldehydes, hydrazine monohydrate, ethyl acetoacetate, and malononitrile Catalyst free Water Ultrasound 30–90 s 90–97% Shabalala et al.46
Pyrano[2,3-c]pyrazole-3-carboxylate and pyrano[2,3-c]pyrazole-5-carbonitriles Four-component system: dimethylacetylenedicarboxylate/ethyl acetoacetate, hydrazine hydrate, malononitrile, and aromatic aldehyde Mn/ZrO2 Aq. ethanol Ultrasound 10 min 88–99% Maddila et al.47