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. 2023 May 31;8(9):1160–1176. doi: 10.1016/j.jacbts.2023.03.003

Figure 3.

Figure 3

The Effects of rhNRG-1β on LV and Renal Morphology Assessed by Histology at Week 10

(A) Representative hematoxylin-eosin (HE)-stained slides and picrosirius red/fast green (PSFG)-stained slides of left ventricles. (B) cardiomyocyte cross-sectional areas, (C) perimeters, (D) left ventricular (LV) fibrosis, (E) representative HE-stained slides and PSFG-stained slides of the kidney tissue, (F) glomerular capillary area, (G) tubular lumen area, and (H) kidney interstitial fibrosis. In the case of left ventricles, scale bars represent 50 μm in the HE images and 100 μm in the PSFG images. In the case of kidney tissue, scale bars represent 100 μm in the HE images and 200 μm in the PSFG images. Values are presented as mean ± SEM, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, n = 7-10, one-way analysis of variance, Holm-Sidak post hoc test. Abbreviations as in Figure 1.