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. 2023 May 31;8(9):1160–1176. doi: 10.1016/j.jacbts.2023.03.003

Figure 5.

Figure 5

The Effects of rhNRG-1β on mRNA Expressions in Human Ventricular Cardiac Fibroblasts

(A) Representative 4,6-diamidino-2-phenylindole (DAPI) and αSMA staining of human ventricular cardiac fibroblasts. The mRNA expression of (B)α SMA, alpha-smooth muscle actin; (C)Col 1, collagen 1; (D)Col 3, collagen 3; and LOX1, lysyl oxidase 1 in human ventricular cardiac fibroblasts. Scale bar, 50 μm. Data are expressed as mean ± SEM, n = 6 replicates/group; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.01, one-way analysis of variance, Tukey post hoc test. Ctrl = control; TGF-β = transforming growth factor beta; ErbB3 AB = EbB3 antibody; other abbreviations as in Figure 1.