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. 2023 Sep 27;17:2985–3021. doi: 10.2147/DDDT.S419361

Table 3.

Advantages and Limitations of Some Natural Polymers

Polymer Advantages Limitations References
Alginate
  • Biocompatible and biodegradable

  • Mechanical qualities that may be tuned

  • Low manufacturing costs

  • Absence of therapeutic effects

  • Reduced mechanical properties.

  • Rapid decomposition

[18]
Cellulose
  • Have a 3D high porosity.

  • Biocompatible

  • Hydrophilic shape improves cell attachment, multiplication, and mechanical characteristics

  • Water insoluble

  • Not biodegradable in humans

[19]
Chitosan
  • Hydrophilic architecture encourages cellular attachment, specialization, and multiplication

  • Expensive manufacturing

  • Unpredictable characteristics

  • Harmful to the ecosystem

[20]
Silk
  • Outstanding mechanical characteristics

  • Receives chemical modifications to be physiologically friendly

  • Environmental concerns

[21]
Protein-based polymers
  • Tissue regeneration capacity

  • Immunogenic and allergic potential

[22,23]
Hyaluronic acid
  • Bioactive and biodegradable

  • Weak mechanical properties

  • Speedy degradation rate

[34]