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. 2023 Sep 27;17:2985–3021. doi: 10.2147/DDDT.S419361

Table 4.

Features of Nanofiber Manufacturing Strategies

Strategy Self-Assembly Phase Separation Electrospinning
Status Semi-solid Solid Solid
Physical shape Hydrogel Scaffold Scaffold
Size (nm) 5–20 50–500 50–2000
Benefits
  • Absence of biohazardous solvents

  • 3D structure

  • Simple process

  • Better control of pore size

  • 3D Shape

  • Single manufacturing process

  • Ability to control the pores

Limitations
  • Complex process

  • Expensive

  • Absence of control over the internal structure

  • Inability to conform the 3D architecture.