Table 2.

Cox proportional hazards multivariable models for demographic and tumor characteristics of 601 patients with NMIBC (for Pheno age acceleration).

	10-year overall survival HR (95% CI)	10-year recurrence-free survivala HR (95% CI)
Age	1.08 (1.06–1.10)	1.02 (1.01–1.03)
Pheno age acceleration	1.06 (1.03–1.08)	1.02 (1.00–1.03)
Sex
Male
Female	0.50 (0.33–0.78)
Tumor grade
Low grade
High grade	1.58 (1.15–2.17)	1.49 (1.18–1.88)
Smoking status
Non-smoker
Former-smoker	1.35 (0.82–2.22)	1.56 (1.13–2.15)
Current-smoker	1.87 (1.10–3.16)	1.69 (1.20–2.38)
BCG treatment
No
Yes	0.89 (0.58–1.34)

Abbreviations: CI, confidence interval; HR, hazard ratio; NMIBC, non–muscle-invasive bladder cancer.

^aStratification was used on sex and BCG treatment status for proportional assumption.