Figure 1.

“Cells in slow motion.”¹⁴ (a) Epithelial cell proliferation is much slower in a D₂O-rich medium. The duration of the cell cycle is roughly 17 h under normal (H₂O) conditions and 44 h in water containing 45% D₂O. (b) Independent of the culturing conditions, the actin cytoskeleton (orange) and the nucleus (blue) remain intact. Shown are typical pictures, which suggest that structures are comparable for the different H₂O and D₂O concentrations. Figure adapted from ref (14), Copyright 2021 Schnauß et al. (licensed under CC BY-NC 4.0).