Table 3.
Biopsy finding among the studied groups (N = 121)
| Parameter | Biliary atresia | Neglected BA (n = 40) |
χ2 | P-value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Type I (n = 19) |
Type IIa (n = 2) |
Type II b (n = 45) |
Type III (n = 15) |
|||||||||
| Bile duct proliferation |
n | % | n | % | n | % | n | % | n | % | ||
| Absent | 1 | 5.57 | 0 | 00.00 | 12 | 26.67 | 1 | 6.67 | 4 | 10.00 | 3.22 | 0.084 |
| Present | 18 | 94.73 | 2 | 100.0 | 33 | 37.33 | 14 | 93.33 | 36 | 90.00 | ||
| Bile plugs | ||||||||||||
| Absent | 1 | 5.57 | 0 | 00.00 | 2 | 4.44 | 0 | 00.00 | 0 | 00.00 | 2.77 | 0.596 |
| Present | 18 | 94.73 | 2 | 100.0 | 43 | 95.56 | 15 | 100.0 | 40 | 100.0 | ||
| Portal fibrosis | ||||||||||||
| Present | 19 | 100.0 | 2 | 100.0 | 45 | 100.0 | 15 | 100.0 | 40 | 100.0 | – | – |
| Giant cell hepatitis | ||||||||||||
| Absent | 16 | 84.21 | 2 | 100.0 | 40 | 88.89 | 9 | 60.00 | 34 | 85.00 | 7.41 | 0.115 |
| Present | 3 | 15.79 | 0 | 00.00 | 5 | 11.11 | 6 | 40.00 | 6 | 15.00 | ||
| Rosetting | ||||||||||||
| Absent | 5 | 26.32 | 0 | 00.00 | 27 | 60.00 | 6 | 40.00 | 15 | 37.5 | 9.44 | 0.051 |
| Present | 14 | 73.68 | 2 | 100.0 | 18 | 40.00 | 9 | 60.00 | 25 | 62.5 | ||
| Degree of fibrosis | ||||||||||||
| Fibrous < 50% | 8 | 42.11 | 2 | 100.0 | 18 | 40.00 | 4 | 26.67 | 26 | 65.00 | ||
| Absent or minimal fibrous expansion |
2 | 10.53 | 0 | 00.00 | 16 | 35.00 | 1 | 6.67 | 14 | 35.00 | 46.85 | < 0.001* |
| Fibrous > 50% (Focal porto- portal bridging) |
7 | 36.48 | 0 | 00.00 | 11 | 24.44 | 10 | 66.67 | 0 | 00.00 | ||
| Marked bridging (cirrhosis) |
2 | 10.53 | 0 | 00.00 | 0 | 00.00 | 0 | 00.00 | 0 | 00.00 | ||
*
Significant