Table 5.
Biopsy finding among the studied groups (N = 81)
Parameter | Diagnosis | χ2 | P-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Biliary atresia | ||||||||||
Type I (n = 19) |
Type II a (n = 2) |
Type II b (n = 45) |
Type III (n = 15) |
|||||||
n | % | n | % | n | % | n | % | |||
Bile duct proliferation | ||||||||||
Absent | 1 | 5.26 | 0 | 0.00 | 12 | 26.67 | 1 | 6.67 | 6.292 | 0.098 |
Present | 18 | 94.74 | 2 | 100 | 33 | 73.33 | 14 | 93.33 | ||
Bile plugs | ||||||||||
Absent | 1 | 5.26 | 0 | 0.00 | 2 | 4.44 | 0 | 0.00 | 0.853 | 0.837 |
Present | 18 | 94.74 | 2 | 100 | 43 | 95.56 | 15 | 100 | ||
Portal fibrosis | ||||||||||
Absent | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | 0 | – | – | |
Present | 19 | 100 | 2 | 100 | 45 | 100 | 15 | 100 | ||
Giant cell hepatitis | ||||||||||
Absent | 16 | 84.21 | 2 | 100 | 40 | 88.89 | 9 | 60.00 | 7.061 | 0.070 |
Present | 3 | 15.79 | 0 | 0.00 | 5 | 11.11 | 6 | 40.00 | ||
Rosetting | ||||||||||
Absent | 5 | 26.32 | 0 | 0.00 | 27 | 60.00 | 6 | 60.00 | 8.386 | 0.039* |
Present | 14 | 73.68 | 2 | 100 | 18 | 40.00 | 9 | 40.00 | ||
Degree of fibrosis | ||||||||||
Fibrous < 50% | 8 | 42.11 | 2 | 100 | 18 | 40.00 | 4 | 26.67 | 21.999 | 0.009* |
Absent or minimal fibrous expansion | 2 | 10.53 | 0 | 0.00 | 16 | 35.56 | 1 | 6.67 | ||
Fibrous > 50% (focal porto-portal bridging) |
7 | 36.84 | 0 | 0.00 | 11 | 24.44 | 10 | 66.67 | ||
Marked bridging (cirrhosis) | 2 | 10.53 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 | ||
Significant