Table 9.
Biopsy finding in relation to APRI score and FIB-4 (N = 81)
Parameter | APRI score | FIB-4 | ||
---|---|---|---|---|
Mean ±SD | P-value | Mean ±SD | P-value | |
Bile duct proliferation | ||||
Absent | 1.80 ±1.44 | 0.211 | 15.71 ±21.96 | 0.331 |
Present | 1.28 ±0.72 | 9.69 ±9.34 | ||
Bile plugs | ||||
Absent | 0.48 ±0.14 | <0.001* | 3.96 ±0.47 | < 0.001* |
Present | 1.41 ±0.90 | 10.99 ±12.64 | ||
Portal fibrosis | ||||
Present | 1.37 ±0.90 | – | 10.73 ±12.47 | – |
Giant cell hepatitis | ||||
Absent | 1.39 ±0.93 | 0.691 | 11.07 ±13.46 | 0.384 |
Present | 1.29 ±0.77 | 9.09 ±5.75 | ||
Rosetting | ||||
Absent | 1.48 ±0.97 | 0.311 | 9.75 ±5.97 | 0.490 |
Present | 1.28 ±0.82 | 11.59 ±16.22 | ||
Degree of fibrosis | ||||
Fibrous expansion of most portal tracts | 1.71 ±1.09 | 0.055 | 10.98 ±5.76 | 0.485 |
Absent or fibrous expansion of some portal tracts | 1.17 ±0.78 | 14.07 ±23.92 | ||
Focal porto-portal bridging | 1.15 ±0.59 | 8.26 ±4.98 | ||
Marked bridging | 1.01 ±0.89 | 9.55 ±7.73 |
Significant