Table 2.
Top ten genes closest to common insertion sites for each cell population using RIPAT analysis for two donors transduced with LV2 alone (untreated) or in combination with GSK2622391 or compound B, compared to a polyclonal HEK cell line
| Donor 1 |
Donor 2 |
Polyclonal HEK | ||||
|---|---|---|---|---|---|---|
| Compound A | Compound B | Untreated | Compound A | Compound B | Untreated | |
| PACS1 | NPLOC4 | NPLOC4 | KDM2A | PACS1 | HSF1 | RP11-953B20.2 |
| NPLOC4 | PACS1 | BOP1 | BOP1 | JPT2 | NPLOC4 | TBC1D22A |
| KDM2A | SBF1 | MAPK8IP3 | SCX | POLR2E | NOSIP | CDC42BPG |
| BAG6 | MAPK8IP3 | ZNF34 | PACS1 | NOSIP | PRRG2 | NPLOC4 |
| MAPK8IP3 | ABCA7 | POLR2A | NPLOC4 | PRRG2 | PACS1 | TSPAN10 |
| BOP1 | MROH1 | MSH5 | JPT2 | NPLOC4 | KDM2A | MAPK8IP3 |
| SBNO2 | LTA | MSH5-SAPCD1 | SBNO2 | KDM2A | TNRC6C | TRAF2 |
| TRAF2 | TRAF7 | KDM2A | ALYREF | BOP1 | ARHGAP45 | ZGPAT |
| PPP6R2 | VWA7 | SBF1 | PPP1R2P1 | PRRC2A | MAPK8IP3 | RP4-583P15.15 |
| PSMB9 | TNRC6C | RP11-953B20.2 | SBF1 | SBF1 | IL32 | TNFSF12 |