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. 2023 Oct 2;24:370. doi: 10.1186/s12859-023-05452-4

Fig. 5.

Fig. 5

Comparison of FLARE to RNAEditor. A ADAR1-knockdown leads to a decrease in cluster counts B Clusters in the ADAR1-knockdown condition have lower edit fractions. C Replicable clusters also conform to the expected trend. D FLARE recapitulates a majority of RNAEditor “editing islands.” E The additional clusters found by FLARE but not RNAEditor tend to be of lower edit fraction, reflecting FLARE’s increased sensitivity. F FLARE-exclusive clusters exhibit the expected decrease in overlap fraction with Alu elements