Table 2.
Overview of the Strength of Evidence per Factor
| Factor | # Studies | Strength of Evidence for Association with Neurocognitive Recovery |
|---|---|---|
| Smoking | 8 | Sufficient & associated |
| Quantities used | 13 | Sufficient & not associated |
| Polysubstance | 4 | Limited & not associated |
| Detoxifications | 3 | Limited |
| Positive family history | 5 | Limited |
| Age | 10 | Sufficient & inconsistent |
| Gender | 3 | Limited & not associated |
| Education | 6 | Sufficient & not associated |
| Depression | 7 | Limited |
| ASPD | 2 | Limited |
| Verbal reading | 5 | Limited & not associated |
| Blood values | 3 | Limited |
| Neurocognitive task | 1 | Limited |
| Medical conditions | 3 | Limited |
| Brain volumes | 6 | Sufficient & associated |
| Perfusion | 1 | Limited |
Notes: Sufficient & associated = enough studies, consistent pattern of associations with recovery of neurocognitive functions; Sufficient & not associated = enough studies, consistent pattern of not being associated with recovery of neurocognitive function; limited and not associated = not enough studies, most studies show no associations with recovery of neurocognitive functions; Limited = not enough studies; Sufficient & inconsistent = enough studies with mixed results.