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. 2023 Sep 29;11:e16155. doi: 10.7717/peerj.16155

Figure 1. Effect of FXR knockout on body weight, body fat, blood glucose, insulin sensitivity, urine output and urine osmolarity in db/db mice.

Figure 1

(A) Body weight of four types of mice: FXR+/+db/db (n = 4), FXR−/−db/db (n = 4), FXR+/+db/m (n = 6), and FXR−/−db/m (n = 6). (B) Random blood glucose results. (C) Results of body fat, body fat percentage. (D) Results of ITT and OGTT tests (E) Results of 24 h urine volume and urine osmolality. Data are presented as mean ±SEM.∗P < 0.05,∗∗P < 0.01,∗∗∗P < 0.001 vs. FXR+/+;#P < 0.05,##P < 0.01, ###P < 0.001 vs. db/m.