Figure 3. Real-time PCR and Western blot results of associated factors in four types of mice.

(A) Changes in the mRNA levels of fibrosis factor, TGF β1-Smad pathway-related factors, and FXR chaperone SHP in four types of mice (n = 3). (B) Changes in protein levels of fibrosis factor, TGF β1-Smad pathway-related factors and FXR chaperone SHP (n = 3). Data are presented as mean ±SEM. ^∗P < 0.05,^∗∗P < 0.01,^∗∗∗P < 0.001 vs. FXR^+/+;^#P < 0.05,^##P < 0.01 vs. db/m.