Table 1. Biochemical analyses of the mice in the four type mice.

	FXR+/+db/db	FXR−/−db/db	FXR+/+db/m	FXR−/−db/m
Urea (mmol/L)	10.4 ±1.2a	15.3 ±0.2b	3.5 ±0.4	6.4 ±0.5a
Cr (umol/L)	24.7 ±4.0a	37.1 ±4.0b	12.8 ±1.3	18.5 ±2.8a
UA (umol/L)	295.7 ±67.3a	384.0 ±71.2b	160.1 ±12.0	196.2 ±23.0a
Proteinuria (mg)	2,010.2 ±191.1a	3,412.0 ±162.9b	625.2 ±21.7	1,437.9 ±23.7a

Notes.

Abbreviations: data are expressed as the mean ±SEM.

^aP < 0.01 vs. FXR+/+db/m.

^bP < 0.05 vs. FXR+/+db/db,

n, 4-6 per group.