Table 5.

Showing the differences in heart rate during the first, second and third scan acquisitions

Heart rate (bpm)	Scan 1 vs scan 2			Scan 1 vs scan 3			Scan 2 vs scan 3
	Mean diff	P-value	95% CI of diff	Mean diff	P-value	95% CI of diff	Mean diff	P-value	95% CI of diff
All	1 ± 3	0.01	0, 2	1 ± 3	0.02	0, 3	0 ± 2	0.82	− 1, 1
Healthy	1 ± 3	0.19	0, 2	0 ± 4	0.75	− 1, 2	− 1 ± 2	0.06	− 1, 0
Patient (standardised AW)	1 ± 2	0.04	0, 1	1 ± 2	0.17	0, 1	− 0 ± 1	0.28	− 1, 0
Patient (variable AW)	2 ± 3	< 0.01	1, 3	3 ± 3	< 0.01	2, 5	1 ± 1	< 0.01	1, 2

	Scan 1			Scan 2			Scan 3
	Mean diff	P-value	95% CI of diff	Mean diff	P-value	95% CI of diff	Mean diff	P-value	95% CI of diff
Healthy vs patient (all)	8 (4)	0.04	1, 16	9 (4)	0.04	1, 17	10 (4)	0.02	2, 18
Patient (standard AW) vs patient (variable AW)	2 (4)	0.67	− 6, 9	3 (3)	0.36	− 4, 10	4 (3)	0.18	− 2, 11

This is further compared between the whole cohort and the healthy and patient participants. The mean difference was analysed using a one-sample t-test and presented as mean ± SD. Unpaired data was analysed using Welch’s t test and presented as mean and standard error. Statistically significant values (p<0.05) are indicated in bold